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Glucolipotoxicity initiates pancreatic ß-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation.
Bagnati, Marta; Ogunkolade, Babatunji W; Marshall, Catriona; Tucci, Carmen; Hanna, Katie; Jones, Tania A; Bugliani, Marco; Nedjai, Belinda; Caton, Paul W; Kieswich, Julius; Yaqoob, Muhammed M; Ball, Graham R; Marchetti, Piero; Hitman, Graham A; Turner, Mark D.
Afiliação
  • Bagnati M; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Ogunkolade BW; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Marshall C; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Tucci C; Interdisciplinary Biomedical Research Centre, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
  • Hanna K; Interdisciplinary Biomedical Research Centre, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
  • Jones TA; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Bugliani M; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Nedjai B; Leukocyte Biology Section, National Heart and Lung Institute, Imperial College, London, UK.
  • Caton PW; Diabetes and Nutritional Sciences Division, School of Medicine, King's College London, London, UK.
  • Kieswich J; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Yaqoob MM; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Ball GR; Interdisciplinary Biomedical Research Centre, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
  • Marchetti P; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
  • Hitman GA; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Turner MD; Interdisciplinary Biomedical Research Centre, School of Science and Technology, Nottingham Trent University, Nottingham, UK.
Cell Death Dis ; 7(8): e2329, 2016 08 11.
Article em En | MEDLINE | ID: mdl-27512950
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_pancreatic_cancer Assunto principal: NF-kappa B / Antígenos CD40 / Células Secretoras de Insulina / Fator de Transcrição STAT1 / Glucose / Lipídeos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_pancreatic_cancer Assunto principal: NF-kappa B / Antígenos CD40 / Células Secretoras de Insulina / Fator de Transcrição STAT1 / Glucose / Lipídeos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido