New Isocoumarins and Related Metabolites from Talaromyces flavus.
Nat Prod Commun
; 11(6): 805-8, 2016 Jun.
Article
em En
| MEDLINE
| ID: mdl-27534122
ABSTRACT
Two new isocoumarin derivatives, talaisocoumarins A (1) and B (2), and three new related metabolites, talaflavuols A-C (3-5) were isolated from the wetland soil-derived fungus Talaromyces flavus BYD07-13. Their structures were elucidated by spectroscopic (NMR) and MS analyses. The absolute configurations of 1 and 2 were determined by CD and an Rh2(OCOCF3)4-induced CD method. All compounds were evaluated for cytotoxic and antimicrobial activities. However, none of them showed any activity. The plausible biosynthetic pathways for 1-5 were also proposed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Talaromyces
/
Isocumarinas
Idioma:
En
Revista:
Nat Prod Commun
Assunto da revista:
BOTANICA
/
FARMACOLOGIA
/
QUIMICA
Ano de publicação:
2016
Tipo de documento:
Article