A Naturalistic Evaluation of Extended-Release Naltrexone in Clinical Practice in Missouri.
J Subst Abuse Treat
; 70: 50-57, 2016 11.
Article
em En
| MEDLINE
| ID: mdl-27692188
ABSTRACT
The purpose of this study was to compare the naturalistic outcomes of individuals with alcohol or opioid use problems who were treated with extended-release naltrexone (XR-NTX) to those treated with psychosocial treatment only and also to those treated with other medication-assisted therapies in Missouri during 2010 to 2011. We analyzed intake and discharge data collected as part of SAMHSA's Treatment Episode Data Set assessments. Patients who received XR-NTX during their treatment episode were compared, for those reporting alcohol (but not opioids) as their problem (N=21,137), to those who received oral naltrexone, acamprosate, and psychosocial treatment only, and for those who reported opioids as a problem (N=8996), to those receiving oral naltrexone, buprenorphine/naloxone, and psychosocial treatment only. Group differences were adjusted using propensity score weighting, with propensity scores derived from 18 intake variables. For the alcohol sample, patients who received XR-NTX vs. the oral naltrexone group had superior composite outcomes on a measure combining abstinence, self-help participation, employment, and arrests. For the opioid sample, XR-NTX was found to have significantly better outcomes than oral naltrexone on the composite outcome measure. For both the alcohol and opioid samples, the group that received XR-NTX stayed in treatment longer vs. psychosocial treatment only. In the opioid sample, those receiving buprenorphine/naloxone remained in treatment longer than those receiving XR-NTX.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
2_ODS3
/
8_ODS3_consumo_sustancias_psicoactivas
Problema de saúde:
2_sustancias_psicoativas
/
8_alcohol
/
8_opioid_abuse
Assunto principal:
Psicoterapia
/
Taurina
/
Avaliação de Resultados em Cuidados de Saúde
/
Transtornos Relacionados ao Uso de Álcool
/
Dissuasores de Álcool
/
Naltrexona
/
Antagonistas de Entorpecentes
/
Transtornos Relacionados ao Uso de Opioides
Tipo de estudo:
Evaluation_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
America do norte
Idioma:
En
Revista:
J Subst Abuse Treat
Assunto da revista:
TRANSTORNOS RELACIONADOS COM SUBSTANCIAS
Ano de publicação:
2016
Tipo de documento:
Article