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Amiselimod, a novel sphingosine 1-phosphate receptor-1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia risk.
Sugahara, Kunio; Maeda, Yasuhiro; Shimano, Kyoko; Mogami, Akira; Kataoka, Hirotoshi; Ogawa, Kei; Hikida, Kumiko; Kumagai, Hiroshi; Asayama, Mahoko; Yamamoto, Toshinobu; Harada, Tomohiko; Ni, Pingping; Inoue, Shinsuke; Kawaguchi, Atsuhiro.
Afiliação
  • Sugahara K; Research Unit/Frontier Therapeutic Sciences, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.
  • Maeda Y; Research Unit/Frontier Therapeutic Sciences, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.
  • Shimano K; Research Unit/Frontier Therapeutic Sciences, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.
  • Mogami A; Research Unit/Frontier Therapeutic Sciences, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.
  • Kataoka H; Research Unit/Frontier Therapeutic Sciences, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.
  • Ogawa K; DMPK Research Laboratories, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.
  • Hikida K; DMPK Research Laboratories, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.
  • Kumagai H; DMPK Research Laboratories, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.
  • Asayama M; Safety Research Laboratories, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Saitama, Japan.
  • Yamamoto T; Safety Research Laboratories, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Saitama, Japan.
  • Harada T; Mitsubishi Tanabe Pharma Europe, Dashwood House, London, UK.
  • Ni P; Mitsubishi Tanabe Pharma Europe, Dashwood House, London, UK.
  • Inoue S; Data Science Department, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Tokyo, Japan.
  • Kawaguchi A; Data Science Department, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Tokyo, Japan.
Br J Pharmacol ; 174(1): 15-27, 2017 01.
Article em En | MEDLINE | ID: mdl-27714763
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Organofosfatos / Propanolaminas / Doenças Autoimunes / Bradicardia / Receptores de Lisoesfingolipídeo Tipo de estudo: Clinical_trials / Etiology_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Organofosfatos / Propanolaminas / Doenças Autoimunes / Bradicardia / Receptores de Lisoesfingolipídeo Tipo de estudo: Clinical_trials / Etiology_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão