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Antileukemic Scalarane Sesterterpenoids and Meroditerpenoid from Carteriospongia (Phyllospongia) sp., Induce Apoptosis via Dual Inhibitory Effects on Topoisomerase II and Hsp90.
Lai, Kuei-Hung; Liu, Yi-Chang; Su, Jui-Hsin; El-Shazly, Mohamed; Wu, Chih-Fung; Du, Ying-Chi; Hsu, Yu-Ming; Yang, Juan-Cheng; Weng, Ming-Kai; Chou, Chia-Hua; Chen, Guan-Yu; Chen, Yu-Cheng; Lu, Mei-Chin.
Afiliação
  • Lai KH; Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung, 944, Taiwan.
  • Liu YC; National Museum of Marine Biology &Aquarium, Pingtung 944, Taiwan.
  • Su JH; Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
  • El-Shazly M; Division of Pharmacognosy, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden.
  • Wu CF; Division of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, 807, Taiwan.
  • Du YC; Department of Internal Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.
  • Hsu YM; Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung, 944, Taiwan.
  • Yang JC; National Museum of Marine Biology &Aquarium, Pingtung 944, Taiwan.
  • Weng MK; Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, Ain-Shams University, Organization of African Unity Street, Abassia, Cairo 11566, Egypt.
  • Chou CH; Division of Surgical Oncology, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
  • Chen GY; Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung, 944, Taiwan.
  • Chen YC; National Museum of Marine Biology &Aquarium, Pingtung 944, Taiwan.
  • Lu MC; Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Sci Rep ; 6: 36170, 2016 10 31.
Article em En | MEDLINE | ID: mdl-27796344
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_leukemia Assunto principal: Poríferos / DNA Topoisomerases Tipo II / Proteínas de Choque Térmico HSP90 / Diterpenos / Sesterterpenos Limite: Animals / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Taiwan
Texto completo
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Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_leukemia Assunto principal: Poríferos / DNA Topoisomerases Tipo II / Proteínas de Choque Térmico HSP90 / Diterpenos / Sesterterpenos Limite: Animals / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Taiwan