Dysfunction of endothelial progenitor cells in hyperlipidemic rats involves the increase of NADPH oxidase derived reactive oxygen species production.

Li, Ting-Bo; Zhang, Jie-Jie; Liu, Bin; Luo, Xiu-Ju; Ma, Qi-Lin; Peng, Jun

Li, Ting-Bo; Zhang, Jie-Jie; Liu, Bin; Luo, Xiu-Ju; Ma, Qi-Lin; Peng, Jun.

Afiliação

Li TB; a Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Zhang JJ; a Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Liu B; a Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Luo XJ; b Department of Laboratory Medicine, Xiangya School of Medicine, Central South University, Changsha 410013, China.
Ma QL; c Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
Peng J; a Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.

Can J Physiol Pharmacol ; 95(5): 474-480, 2017 May.

Article em En | MEDLINE | ID: mdl-28177697

Assuntos

Células Progenitoras Endoteliais/efeitos dos fármacos; Células Progenitoras Endoteliais/metabolismo; Hiperlipidemias/metabolismo; Hiperlipidemias/patologia; NADPH Oxidases/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Animais; Células Progenitoras Endoteliais/patologia; Inibidores Enzimáticos/farmacologia; Hiperlipidemias/induzido quimicamente; Lipoproteínas LDL/farmacologia; Masculino; NADPH Oxidases/antagonistas & inibidores; Fenótipo; Ratos; Ratos Sprague-Dawley

Palavras-chave

NADPH oxidase; NADPH oxydase; cellules endothéliales progénitrices; dérivés réactifs de l'oxygène; endothelial progenitor cells; hyperlipidemia; hyperlipidémie; lipoprotéines de basse densité oxydées; oxidized low-density lipoprotein; reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espécies Reativas de Oxigênio / NADPH Oxidases / Células Progenitoras Endoteliais / Hiperlipidemias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Can J Physiol Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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