The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways.

Vajjhala, Parimala R; Ve, Thomas; Bentham, Adam; Stacey, Katryn J; Kobe, Bostjan

Vajjhala, Parimala R; Ve, Thomas; Bentham, Adam; Stacey, Katryn J; Kobe, Bostjan.

Afiliação

Vajjhala PR; School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.
Ve T; School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia; Institute for Glycomics, Griffith University, Southport, QLD 4222, Australia.
Bentham A; School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia; School of Biological Sciences, Flinders University, Adelaide, SA 5001, Australia.
Stacey KJ; School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.
Kobe B; School of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address: b.kobe@uq.edu.au.

Mol Immunol ; 86: 23-37, 2017 06.

Article em En | MEDLINE | ID: mdl-28249680

Assuntos

Imunidade Inata; Inflamassomos/imunologia; Proteínas NLR/metabolismo; Receptores de Reconhecimento de Padrão/metabolismo; Transdução de Sinais/imunologia; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Animais; Domínio de Ativação e Recrutamento de Caspases; Proteína DEAD-box 58/metabolismo; Fungos/fisiologia; Humanos; Proteínas NLR/química; Plantas/imunologia; Receptores Imunológicos; Receptores de Reconhecimento de Padrão/química; Receptores Toll-Like/metabolismo

Palavras-chave

Higher-order assembly signaling; Inflammasome; Leucine-rich repeat-containing/nucleotide and oligomerization domain-like receptor (NLR); Nucleotide binding and oligomerization domain; RIG-1-like receptor (RLR); Signaling by co-operative assembly formation (SCAF); Toll-like receptor (TLR)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Receptores de Reconhecimento de Padrão / Inflamassomos / Proteínas NLR / Imunidade Inata Limite: Animals / Humans Idioma: En Revista: Mol Immunol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Austrália

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