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Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers.
Kuchenbaecker, Karoline B; McGuffog, Lesley; Barrowdale, Daniel; Lee, Andrew; Soucy, Penny; Dennis, Joe; Domchek, Susan M; Robson, Mark; Spurdle, Amanda B; Ramus, Susan J; Mavaddat, Nasim; Terry, Mary Beth; Neuhausen, Susan L; Schmutzler, Rita Katharina; Simard, Jacques; Pharoah, Paul D P; Offit, Kenneth; Couch, Fergus J; Chenevix-Trench, Georgia; Easton, Douglas F; Antoniou, Antonis C.
Afiliação
  • Kuchenbaecker KB; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
  • McGuffog L; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Barrowdale D; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Lee A; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Soucy P; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Dennis J; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Quebec, Canada.
  • Domchek SM; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Robson M; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Spurdle AB; Clinical Genetics, Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ramus SJ; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Mavaddat N; School of Women's and Children's Health, University of New South Wales, Australia; The Kinghorn Cancer Centre, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia.
  • Terry MB; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
  • Neuhausen SL; Department of Epidemiology, Columbia University, New York, NY, USA.
  • Schmutzler RK; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA.
  • Simard J; Center for Hereditary Breast and Ovarian Cancer and Center for Integrated Oncology, Medical Faculty, University Hospital Cologne, Germany.
  • Pharoah PDP; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Quebec, Canada.
  • Offit K; Department of Oncology, University of Cambridge, Cambridge, UK.
  • Couch FJ; Clinical Genetics Research Laboratory, Department of Medicine, Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
  • Chenevix-Trench G; Department of Laboratory Medicine and Pathology, and Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
  • Easton DF; Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
  • Antoniou AC; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
J Natl Cancer Inst ; 109(7)2017 07 01.
Article em En | MEDLINE | ID: mdl-28376175
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias da Mama / Genes BRCA1 / Genes BRCA2 / Mutação Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Middle aged Idioma: En Revista: J Natl Cancer Inst Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias da Mama / Genes BRCA1 / Genes BRCA2 / Mutação Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Middle aged Idioma: En Revista: J Natl Cancer Inst Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido