Your browser doesn't support javascript.
loading
Anti-inflammatory Flavan-3-ol-dihydroretrochalcones from Daemonorops draco.
Kuo, Ping-Chung; Hung, Hsin-Yi; Hwang, Tsong-Long; Du, Wen-Ke; Ku, Hsiang-Chih; Lee, E-Jian; Tai, Shih-Huang; Chen, Fu-An; Wu, Tian-Shung.
Afiliação
  • Kuo PC; School of Pharmacy, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University , Tainan 701, Taiwan.
  • Hung HY; School of Pharmacy, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University , Tainan 701, Taiwan.
  • Hwang TL; Graduate Institute of Natural Products, College of Medicine, Chang Gung University ; Research Center for Chinese Herbal Medicine, Research Center for Food and Cosmetic Safety, and Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technol
  • Du WK; School of Pharmacy, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University , Tainan 701, Taiwan.
  • Ku HC; Graduate Institute of Natural Products, College of Medicine, Chang Gung University ; Research Center for Chinese Herbal Medicine, Research Center for Food and Cosmetic Safety, and Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technol
  • Lee EJ; Department of Surgery and Anesthesiology, and Institute of Biomedical Engineering, National Cheng Kung University, Medical Center and Medical School , Tainan 701, Taiwan.
  • Tai SH; Department of Surgery and Anesthesiology, and Institute of Biomedical Engineering, National Cheng Kung University, Medical Center and Medical School , Tainan 701, Taiwan.
  • Chen FA; Department of Pharmacy, College of Pharmacy and Health Care, Tajen University , Pingtung 907, Taiwan.
  • Wu TS; School of Pharmacy, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University , Tainan 701, Taiwan.
J Nat Prod ; 80(4): 783-789, 2017 04 28.
Article em En | MEDLINE | ID: mdl-28398735
Four A-type flavan-3-ol-dihydroretrochalcone dimers, dragonins A-D (1-4), were characterized from the traditional Chinese medicine Sanguis Draconis. The structures of 1-4 were elucidated by spectroscopic and spectrometric analyses. Compounds 1 and 2 exhibited significant inhibition of fMLP/CB-induced superoxide anion and elastase. The signaling pathways accounting for the inhibitory effects of compound 2 were also elucidated. These purified A-type flavan-3-ol-dihydroretrochalcones are new potential leads for the development of anti-inflammatory drugs.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resinas Vegetais / Flavonoides / Chalconas / Anti-Inflamatórios Limite: Humans Idioma: En Revista: J Nat Prod Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resinas Vegetais / Flavonoides / Chalconas / Anti-Inflamatórios Limite: Humans Idioma: En Revista: J Nat Prod Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan