Your browser doesn't support javascript.
loading
Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis.
Desroy, Nicolas; Housseman, Christopher; Bock, Xavier; Joncour, Agnès; Bienvenu, Natacha; Cherel, Laëtitia; Labeguere, Virginie; Rondet, Emilie; Peixoto, Christophe; Grassot, Jean-Marie; Picolet, Olivier; Annoot, Denis; Triballeau, Nicolas; Monjardet, Alain; Wakselman, Emanuelle; Roncoroni, Veronique; Le Tallec, Sandrine; Blanque, Roland; Cottereaux, Celine; Vandervoort, Nele; Christophe, Thierry; Mollat, Patrick; Lamers, Marieke; Auberval, Marielle; Hrvacic, Boska; Ralic, Jovica; Oste, Line; van der Aar, Ellen; Brys, Reginald; Heckmann, Bertrand.
Afiliação
  • Desroy N; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Housseman C; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Bock X; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Joncour A; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Bienvenu N; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Cherel L; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Labeguere V; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Rondet E; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Peixoto C; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Grassot JM; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Picolet O; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Annoot D; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Triballeau N; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Monjardet A; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Wakselman E; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Roncoroni V; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Le Tallec S; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Blanque R; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Cottereaux C; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Vandervoort N; Galapagos NV , Generaal De Wittelaan L11 A3, 2800 Mechelen, Belgium.
  • Christophe T; Galapagos NV , Generaal De Wittelaan L11 A3, 2800 Mechelen, Belgium.
  • Mollat P; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Lamers M; Charles River Laboratories , Chesterford Research Park, CB10 1XL Saffron Walden, United Kingdom.
  • Auberval M; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Hrvacic B; Fidelta Ltd. , Prilaz baruna Filipovica 29, Zagreb, HR-10000, Croatia.
  • Ralic J; Fidelta Ltd. , Prilaz baruna Filipovica 29, Zagreb, HR-10000, Croatia.
  • Oste L; Galapagos NV , Generaal De Wittelaan L11 A3, 2800 Mechelen, Belgium.
  • van der Aar E; Galapagos NV , Generaal De Wittelaan L11 A3, 2800 Mechelen, Belgium.
  • Brys R; Galapagos NV , Generaal De Wittelaan L11 A3, 2800 Mechelen, Belgium.
  • Heckmann B; Galapagos SASU , 102 Avenue Gaston Roussel, 93230 Romainville, France.
J Med Chem ; 60(9): 3580-3590, 2017 05 11.
Article em En | MEDLINE | ID: mdl-28414242
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Diester Fosfórico Hidrolases / Fibrose Pulmonar Idiopática / Imidazóis Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Diester Fosfórico Hidrolases / Fibrose Pulmonar Idiopática / Imidazóis Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França