Development of novel in silico model for developmental toxicity assessment by using naïve Bayes classifier method.

Zhang, Hui; Ren, Ji-Xia; Kang, Yan-Li; Bo, Peng; Liang, Jun-Yu; Ding, Lan; Kong, Wei-Bao; Zhang, Ji

Zhang, Hui; Ren, Ji-Xia; Kang, Yan-Li; Bo, Peng; Liang, Jun-Yu; Ding, Lan; Kong, Wei-Bao; Zhang, Ji.

Afiliação

Zhang H; College of Life Science, Northwest Normal University, Lanzhou, Gansu, 730070, PR China; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, 610041, PR China. Electronic address: zhanghui123gansu@163.com.
Ren JX; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, 610041, PR China; College of Life Science, Liaocheng University, Liaocheng, Shandong, 252059, PR China.
Kang YL; College of Life Science, Northwest Normal University, Lanzhou, Gansu, 730070, PR China.
Bo P; College of Life Science, Northwest Normal University, Lanzhou, Gansu, 730070, PR China.
Liang JY; College of Life Science, Northwest Normal University, Lanzhou, Gansu, 730070, PR China.
Ding L; College of Life Science, Northwest Normal University, Lanzhou, Gansu, 730070, PR China. Electronic address: dinglan@nwnu.edu.cn.
Kong WB; College of Life Science, Northwest Normal University, Lanzhou, Gansu, 730070, PR China.
Zhang J; College of Life Science, Northwest Normal University, Lanzhou, Gansu, 730070, PR China.

Reprod Toxicol ; 71: 8-15, 2017 08.

Article em En | MEDLINE | ID: mdl-28428071

Assuntos

Teorema de Bayes; Modelos Biológicos; Teratogênicos/toxicidade; Simulação por Computador; Teratogênicos/química

Palavras-chave

Developmental toxicity; Extended connectivity fingerprints (ECFP_6); In silico prediction; Molecular descriptors; Naïve Bayes classifier

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Teratogênicos / Teorema de Bayes / Modelos Biológicos Tipo de estudo: Prognostic_studies Idioma: En Revista: Reprod Toxicol Assunto da revista: EMBRIOLOGIA / MEDICINA REPRODUTIVA / TOXICOLOGIA Ano de publicação: 2017 Tipo de documento: Article

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