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Estimation of Interindividual Variability of Pharmacokinetics of CYP2C9 Substrates in Humans.
Chiba, Koji; Shimizu, Keiko; Kato, Motohiro; Miyazaki, Taichi; Nishibayashi, Takaaki; Terada, Kazuki; Sugiyama, Yuichi.
Afiliação
  • Chiba K; Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama-shi, Kanagawa 245-0066, Japan; Sugiyama Laboratory, RIKEN Innovation Center, Research Cluster for Innovation, RIKEN, 1-6, Suehiro-cho, Tsurumi-ku, Yokohama-shi, Kanagawa 230-0045, Japan. Electr
  • Shimizu K; DMPK Research Laboratory, Kyorin Pharmaceutical Company, Ltd., Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Kato M; Research Division, Chugai Pharmaceutical Company, Ltd., 1-135 Komakado, Gotemba, Shizuoka 412-8513, Japan.
  • Miyazaki T; Department of Drug Development and Regulatory Science, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan.
  • Nishibayashi T; Department of Drug Development and Regulatory Science, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan.
  • Terada K; Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama-shi, Kanagawa 245-0066, Japan.
  • Sugiyama Y; Sugiyama Laboratory, RIKEN Innovation Center, Research Cluster for Innovation, RIKEN, 1-6, Suehiro-cho, Tsurumi-ku, Yokohama-shi, Kanagawa 230-0045, Japan.
J Pharm Sci ; 106(9): 2695-2703, 2017 09.
Article em En | MEDLINE | ID: mdl-28435143
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Tolbutamida / Citocromo P-450 CYP2C9 / Hipoglicemiantes Tipo de estudo: Health_economic_evaluation / Prognostic_studies Limite: Humans Idioma: En Revista: J Pharm Sci Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Tolbutamida / Citocromo P-450 CYP2C9 / Hipoglicemiantes Tipo de estudo: Health_economic_evaluation / Prognostic_studies Limite: Humans Idioma: En Revista: J Pharm Sci Ano de publicação: 2017 Tipo de documento: Article