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Non invasive imaging assessment of the biodistribution of GSK2849330, an ADCC and CDC optimized anti HER3 mAb, and its role in tumor macrophage recruitment in human tumor-bearing mice.
Alsaid, Hasan; Skedzielewski, Tinamarie; Rambo, Mary V; Hunsinger, Kristen; Hoang, Bao; Fieles, William; Long, Edward R; Tunstead, James; Vugts, Danielle J; Cleveland, Matthew; Clarke, Neil; Matheny, Christopher; Jucker, Beat M.
Afiliação
  • Alsaid H; Bioimaging, Platform Technology & Science, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
  • Skedzielewski T; Bioimaging, Platform Technology & Science, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
  • Rambo MV; Bioimaging, Platform Technology & Science, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
  • Hunsinger K; Bioimaging, Platform Technology & Science, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
  • Hoang B; Target Sciences Target & Pathway, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
  • Fieles W; Target Sciences Target & Pathway, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
  • Long ER; Integrated Biological Platform Sciences, Platform Technology & Science, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
  • Tunstead J; Target Sciences Target & Pathway, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
  • Vugts DJ; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands.
  • Cleveland M; Bioimaging, Platform Technology & Science, GlaxoSmithKline, Stevenage, United Kingdom.
  • Clarke N; Biopharm Molecular Discovery, GlaxoSmithKline, Stevenage, United Kingdom.
  • Matheny C; Immunoginicity and Biomarkers, Platform Technology & Science, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
  • Jucker BM; Bioimaging, Platform Technology & Science, GlaxoSmithKline, King of Prussia, Pennsylvania, United States of America.
PLoS One ; 12(4): e0176075, 2017.
Article em En | MEDLINE | ID: mdl-28448604
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Radiofarmacêuticos / Receptor ErbB-3 / Anticorpos Monoclonais Humanizados / Macrófagos / Anticorpos Monoclonais Limite: Animals / Female / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Radiofarmacêuticos / Receptor ErbB-3 / Anticorpos Monoclonais Humanizados / Macrófagos / Anticorpos Monoclonais Limite: Animals / Female / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos