A new diaryl 1, 2-diketone from the heartwood of Dalbergia latifolia.

Liu, Rong-Hua; Wang, Ding-Qing; Zhang, Pu-Zhao; Shao, Feng; Chen, Lan-Ying; Huang, Hui-Lian; Lin, Shuai

Liu, Rong-Hua; Wang, Ding-Qing; Zhang, Pu-Zhao; Shao, Feng; Chen, Lan-Ying; Huang, Hui-Lian; Lin, Shuai.

Afiliação

Liu RH; a The College of Pharmacy , Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Wang DQ; b Key Laboratory of Innovation Drug and Efficient Energy-saving Pharmaceutical Equipment , Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Zhang PZ; b Key Laboratory of Innovation Drug and Efficient Energy-saving Pharmaceutical Equipment , Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Shao F; b Key Laboratory of Innovation Drug and Efficient Energy-saving Pharmaceutical Equipment , Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Chen LY; c National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine , Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Huang HL; b Key Laboratory of Innovation Drug and Efficient Energy-saving Pharmaceutical Equipment , Jiangxi University of Traditional Chinese Medicine , Nanchang , China.
Lin S; b Key Laboratory of Innovation Drug and Efficient Energy-saving Pharmaceutical Equipment , Jiangxi University of Traditional Chinese Medicine , Nanchang , China.

Nat Prod Res ; 32(1): 91-96, 2018 Jan.

Article em En | MEDLINE | ID: mdl-28602139

ABSTRACT

ABSTRACT

A new diaryl 1,2-diketone, named 1-(2,5-dihydroxy-4-methoxyphenyl)-2-phenylethane-1,2-dione (1), along with eight known compounds (2-9), were isolated from the heartwood of Dalbergia latifolia. They were identified on the basis of spectral data. Compounds 1-7 were obtained from the Dalbergia genus for the first time. Compounds 8 and 9 were firstly isolated from the plant. Compound 1 exhibited inactive against Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC 21530 with the minimum inhibitory concentrations of 10.0 and 10.0 mg/mL, respectively.

Assuntos

Antibacterianos/química; Dalbergia/química; Hidroquinonas/química; Cetonas/química; Antibacterianos/farmacologia; Escherichia coli/efeitos dos fármacos; Hidroquinonas/farmacologia; Cetonas/farmacologia; Espectroscopia de Ressonância Magnética; Testes de Sensibilidade Microbiana; Estrutura Molecular; Staphylococcus aureus/efeitos dos fármacos; Madeira/química

Palavras-chave

1-(2,5-dihydroxy-4-methoxyphenyl)-2-phenylethane-1,2-dione; Dalbergia latifolia; antibacterial activity; diaryl 1,2-diketone

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 3_ND Problema de saúde: 3_neglected_diseases / 3_zoonosis Assunto principal: Dalbergia / Hidroquinonas / Cetonas / Antibacterianos Idioma: En Revista: Nat Prod Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google