Characterization of significant molecular determinants of virulence of Enterovirus 71 sub-genotype B4 in Rhabdomyosarcoma cells.

Yee, Pinn Tsin Isabel; Mohamed, Reham Ahmed Hashim; Ong, Seng-Kai; Tan, Kuan Onn; Poh, Chit Laa

Yee, Pinn Tsin Isabel; Mohamed, Reham Ahmed Hashim; Ong, Seng-Kai; Tan, Kuan Onn; Poh, Chit Laa.

Afiliação

Yee PTI; Research Centre for Biomedical Sciences, School of Science and Technology, Sunway University, Kuala Lumpur, Selangor 47500, Malaysia. Electronic address: isabely@sunway.edu.my.
Mohamed RAH; School of Science and Technology, Department of Biological Sciences, Sunway University, Kuala Lumpur, Selangor 47500, Malaysia. Electronic address: rihoahmed93@gmail.com.
Ong SK; School of Science and Technology, Department of Biological Sciences, Sunway University, Kuala Lumpur, Selangor 47500, Malaysia. Electronic address: ongsk@sunway.edu.my.
Tan KO; School of Science and Technology, Department of Biological Sciences, Sunway University, Kuala Lumpur, Selangor 47500, Malaysia. Electronic address: jefft@sunway.edu.my.
Poh CL; Research Centre for Biomedical Sciences, School of Science and Technology, Sunway University, Kuala Lumpur, Selangor 47500, Malaysia. Electronic address: pohcl@sunway.edu.my.

Virus Res ; 238: 243-252, 2017 06 15.

Article em En | MEDLINE | ID: mdl-28705680

Assuntos

Enterovirus Humano A/crescimento & desenvolvimento; Enterovirus Humano A/genética; Genes Virais; Fatores de Virulência/genética; Replicação Viral; Linhagem Celular Tumoral; Análise Mutacional de DNA; Humanos; RNA Viral/análise; Genética Reversa; Carga Viral; Ensaio de Placa Viral; Proteínas Virais/análise; Virulência

Palavras-chave

Codon deoptimization; Enterovirus 71; Hand foot mouth disease; Mutations; Vaccines; Virulence

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 / 7_ODS3_muertes_prevenibles_nacidos_ninos Problema de saúde: 2_muertes_prevenibles / 7_non_communicable_diseases / 7_nutrition Assunto principal: Replicação Viral / Enterovirus Humano A / Fatores de Virulência / Genes Virais Limite: Humans Idioma: En Revista: Virus Res Assunto da revista: VIROLOGIA Ano de publicação: 2017 Tipo de documento: Article

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