Remote-control of the enantiomeric supramolecular recognition mediated by chiral azobenzenes bound to human serum albumin.
Phys Chem Chem Phys
; 19(32): 21272-21275, 2017 Aug 16.
Article
em En
| MEDLINE
| ID: mdl-28759068
ABSTRACT
Three novel tyrosine-conjugated azobenzene molecules were designed and their ability to target a natural chiral host matrix (human serum albumin, HSA) was investigated. We found that the interplay between the spatial configuration of the chiral substituents and the change in local symmetry resulting from the photoisomerization process strongly affects the optical activity of the bound photochromes. In particular, the different signal amplification obtained upon binding of the photoswitches to the biopolymer enables obtaining a chirooptical system tunable over a wide range of wavelengths.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Azo
/
Albumina Sérica Humana
Limite:
Humans
Idioma:
En
Revista:
Phys Chem Chem Phys
Assunto da revista:
BIOFISICA
/
QUIMICA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Polônia