Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8.

Sagulenko, Vitaliya; Vitak, Nazarii; Vajjhala, Parimala R; Vince, James E; Stacey, Katryn J

Sagulenko, Vitaliya; Vitak, Nazarii; Vajjhala, Parimala R; Vince, James E; Stacey, Katryn J.

Afiliação

Sagulenko V; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Qld 4072, Australia.
Vitak N; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Qld 4072, Australia.
Vajjhala PR; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Qld 4072, Australia.
Vince JE; Walter and Eliza Hall Institute for Medical Research, Parkville, Vic 3052, Australia.
Stacey KJ; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Qld 4072, Australia. Electronic address: katryn.stacey@uq.edu.au.

J Mol Biol ; 430(2): 238-247, 2018 01 19.

Article em En | MEDLINE | ID: mdl-29100888

Assuntos

Caspase 1/imunologia; Caspase 3/imunologia; Caspase 8/imunologia; Proteínas de Ligação a DNA/imunologia; Inflamassomos/imunologia; Animais; Apoptose; Caspase 8/genética; Deleção de Genes; Camundongos Endogâmicos C57BL; Piroptose

Palavras-chave

NLRP3; apoptosis; caspase-8 knockout; cell death; pyroptosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Caspase 1 / Proteínas de Ligação a DNA / Caspase 3 / Caspase 8 / Inflamassomos Limite: Animals Idioma: En Revista: J Mol Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Austrália

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