A randomized, double-blind, active-control trial to evaluate the efficacy and safety of a three day course of tafenoquine monotherapy for the treatment of Plasmodium vivax malaria.

Fukuda, Mark M; Krudsood, Srivicha; Mohamed, Khadeeja; Green, Justin A; Warrasak, Sukhuma; Noedl, Harald; Euswas, Ataya; Ittiverakul, Mali; Buathong, Nillawan; Sriwichai, Sabaithip; Miller, R Scott; Ohrt, Colin

Fukuda, Mark M; Krudsood, Srivicha; Mohamed, Khadeeja; Green, Justin A; Warrasak, Sukhuma; Noedl, Harald; Euswas, Ataya; Ittiverakul, Mali; Buathong, Nillawan; Sriwichai, Sabaithip; Miller, R Scott; Ohrt, Colin.

Afiliação

Fukuda MM; Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
Krudsood S; Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Mohamed K; GlaxoSmithKline Research and Development, Uxbridge, Middlesex, United Kingdom.
Green JA; GlaxoSmithKline Research and Development, Uxbridge, Middlesex, United Kingdom.
Warrasak S; Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Noedl H; Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
Euswas A; Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Ittiverakul M; Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
Buathong N; Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
Sriwichai S; Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
Miller RS; Armed Forces Research Institute of Medical Science, Bangkok, Thailand.
Ohrt C; Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.

PLoS One ; 12(11): e0187376, 2017.

Article em En | MEDLINE | ID: mdl-29121061

Assuntos

Aminoquinolinas/uso terapêutico; Malária Vivax/tratamento farmacológico; Adulto; Aminoquinolinas/sangue; Aminoquinolinas/farmacologia; Animais; Relação Dose-Resposta a Droga; Método Duplo-Cego; Feminino; Febre/complicações; Humanos; Malária Vivax/sangue; Malária Vivax/parasitologia; Masculino; Parasitos/efeitos dos fármacos; Plasmodium vivax; Resultado do Tratamento; Adulto Jovem

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 3_ND Problema de saúde: 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 3_malaria / 3_neglected_diseases Assunto principal: Malária Vivax / Aminoquinolinas Tipo de estudo: Clinical_trials / Guideline Limite: Adult / Animals / Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Tailândia

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