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BIGL: Biochemically Intuitive Generalized Loewe null model for prediction of the expected combined effect compatible with partial agonism and antagonism.
Van der Borght, Koen; Tourny, Annelies; Bagdziunas, Rytis; Thas, Olivier; Nazarov, Maxim; Turner, Heather; Verbist, Bie; Ceulemans, Hugo.
Afiliação
  • Van der Borght K; Discovery Sciences, Janssen Research & Development, Turnhoutseweg 30, B-2340, Beerse, Belgium. kvdborgh@its.jnj.com.
  • Tourny A; Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Coupure Links 653, B-900, Gent, Belgium.
  • Bagdziunas R; Open Analytics, Jupiterstraat 20, B-2600, Antwerpen, Belgium.
  • Thas O; Department of Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Coupure Links 653, B-900, Gent, Belgium.
  • Nazarov M; National Institute for Applied Statistics Research Australia (NIASRA), University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia.
  • Turner H; Open Analytics, Jupiterstraat 20, B-2600, Antwerpen, Belgium.
  • Verbist B; Open Analytics, Jupiterstraat 20, B-2600, Antwerpen, Belgium.
  • Ceulemans H; Discovery Sciences, Janssen Research & Development, Turnhoutseweg 30, B-2340, Beerse, Belgium.
Sci Rep ; 7(1): 17935, 2017 12 20.
Article em En | MEDLINE | ID: mdl-29263342
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antagonismo de Drogas / Quimioterapia Combinada / Agonismo de Drogas / Modelos Teóricos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antagonismo de Drogas / Quimioterapia Combinada / Agonismo de Drogas / Modelos Teóricos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Bélgica