Viral shedding and clinical status of feline-norovirus-infected cats after reinfection with the same strain.
Arch Virol
; 163(6): 1503-1510, 2018 Jun.
Article
em En
| MEDLINE
| ID: mdl-29445988
ABSTRACT
Norovirus (NoV) infection is the most common cause of acute gastroenteritis in humans of all ages worldwide. When cats are experimentally infected with feline norovirus (FNoV), they develop symptoms of acute gastroenteritis. Therefore, FNoV infection may serve as an animal model for the disease caused by human norovirus infection. In this study, we examined whether FNoV of cats infected with genogroup GVI are protected from reinfection with the same strain. The blood anti-FNoV IgG level was inversely correlated with the viral load in stool samples and the clinical score of FNoV-infected cats, but complete prevention of reinfection was not observed. These findings were similar to the results of a reinfection experiment with NoV in human volunteers.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Contexto em Saúde:
2_ODS3
Problema de saúde:
2_enfermedades_transmissibles
Assunto principal:
RNA Viral
/
Eliminação de Partículas Virais
/
Infecções por Caliciviridae
/
Norovirus
/
Proteínas do Capsídeo
/
Gastroenterite
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Arch Virol
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Japão