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Functionally Biased D2R Antagonists: Targeting the ß-Arrestin Pathway to Improve Antipsychotic Treatment.
Weïwer, Michel; Xu, Qihong; Gale, Jennifer P; Lewis, Michael; Campbell, Arthur J; Schroeder, Frederick A; Van de Bittner, Genevieve C; Walk, Michelle; Amaya, Aldo; Su, Ping; D Ordevic, Luka; Sacher, Joshua R; Skepner, Adam; Fei, David; Dennehy, Kelly; Nguyen, Shannon; Faloon, Patrick W; Perez, Jose; Cottrell, Jeffrey R; Liu, Fang; Palmer, Michelle; Pan, Jen Q; Hooker, Jacob M; Zhang, Yan-Ling; Scolnick, Edward; Wagner, Florence F; Holson, Edward B.
Afiliação
  • Weïwer M; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Xu Q; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Gale JP; Center for the Development of Therapeutics , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Lewis M; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Campbell AJ; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Schroeder FA; Department of Radiology, MGH , Athinoula A. Martinos Center for Biomedical Imaging , Charlestown , Massachusetts 02129 , United States.
  • Van de Bittner GC; Department of Radiology, MGH , Athinoula A. Martinos Center for Biomedical Imaging , Charlestown , Massachusetts 02129 , United States.
  • Walk M; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Amaya A; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Su P; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health , University of Toronto , Toronto , Ontario M5T1R8 , Canada.
  • D Ordevic L; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Sacher JR; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Skepner A; Center for the Development of Therapeutics , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Fei D; Center for the Development of Therapeutics , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Dennehy K; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Nguyen S; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Faloon PW; Center for the Development of Therapeutics , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Perez J; Center for the Development of Therapeutics , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Cottrell JR; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Liu F; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health , University of Toronto , Toronto , Ontario M5T1R8 , Canada.
  • Palmer M; Center for the Development of Therapeutics , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Pan JQ; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Hooker JM; Department of Radiology, MGH , Athinoula A. Martinos Center for Biomedical Imaging , Charlestown , Massachusetts 02129 , United States.
  • Zhang YL; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Scolnick E; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Wagner FF; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
  • Holson EB; Stanley Center for Psychiatric Research , Broad Institute of MIT and Harvard , Cambridge , Massachusetts 02142 , United States.
ACS Chem Biol ; 13(4): 1038-1047, 2018 04 20.
Article em En | MEDLINE | ID: mdl-29485852

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antipsicóticos / Receptores de Dopamina D2 / Beta-Arrestinas Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antipsicóticos / Receptores de Dopamina D2 / Beta-Arrestinas Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
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