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Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes.
Lomberk, Gwen; Blum, Yuna; Nicolle, Rémy; Nair, Asha; Gaonkar, Krutika Satish; Marisa, Laetitia; Mathison, Angela; Sun, Zhifu; Yan, Huihuang; Elarouci, Nabila; Armenoult, Lucile; Ayadi, Mira; Ordog, Tamas; Lee, Jeong-Heon; Oliver, Gavin; Klee, Eric; Moutardier, Vincent; Gayet, Odile; Bian, Benjamin; Duconseil, Pauline; Gilabert, Marine; Bigonnet, Martin; Garcia, Stephane; Turrini, Olivier; Delpero, Jean-Robert; Giovannini, Marc; Grandval, Philippe; Gasmi, Mohamed; Secq, Veronique; De Reyniès, Aurélien; Dusetti, Nelson; Iovanna, Juan; Urrutia, Raul.
Afiliação
  • Lomberk G; Division of Research, Department of Surgery, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin, 53226, USA. glomberk@mcw.edu.
  • Blum Y; Programme Cartes d'Identité des Tumeurs (CIT), Ligue Nationale Contre Le Cancer, 14 rue Corvisart, Paris, 75013, France.
  • Nicolle R; Programme Cartes d'Identité des Tumeurs (CIT), Ligue Nationale Contre Le Cancer, 14 rue Corvisart, Paris, 75013, France.
  • Nair A; Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
  • Gaonkar KS; Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
  • Marisa L; Programme Cartes d'Identité des Tumeurs (CIT), Ligue Nationale Contre Le Cancer, 14 rue Corvisart, Paris, 75013, France.
  • Mathison A; Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin, 53226, USA.
  • Sun Z; Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
  • Yan H; Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
  • Elarouci N; Programme Cartes d'Identité des Tumeurs (CIT), Ligue Nationale Contre Le Cancer, 14 rue Corvisart, Paris, 75013, France.
  • Armenoult L; Programme Cartes d'Identité des Tumeurs (CIT), Ligue Nationale Contre Le Cancer, 14 rue Corvisart, Paris, 75013, France.
  • Ayadi M; Programme Cartes d'Identité des Tumeurs (CIT), Ligue Nationale Contre Le Cancer, 14 rue Corvisart, Paris, 75013, France.
  • Ordog T; Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
  • Lee JH; Department of Physiology and Biomedical Engineering, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
  • Oliver G; Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
  • Klee E; Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
  • Moutardier V; Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, 200 First Street SW, Rochester, Minnesota, 55905, USA.
  • Gayet O; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, Marseille, 13288, France.
  • Bian B; Hôpital Nord, Chemin des Bourrely, Marseille, 13015, France.
  • Duconseil P; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, Marseille, 13288, France.
  • Gilabert M; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, Marseille, 13288, France.
  • Bigonnet M; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, Marseille, 13288, France.
  • Garcia S; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, Marseille, 13288, France.
  • Turrini O; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, Marseille, 13288, France.
  • Delpero JR; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, Marseille, 13288, France.
  • Giovannini M; Hôpital Nord, Chemin des Bourrely, Marseille, 13015, France.
  • Grandval P; Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, Marseille, 13288, France.
  • Gasmi M; Institut Paoli-Calmettes, 232 Boulevard Sainte Marguerite, Marseille, 13009, France.
  • Secq V; Institut Paoli-Calmettes, 232 Boulevard Sainte Marguerite, Marseille, 13009, France.
  • De Reyniès A; Institut Paoli-Calmettes, 232 Boulevard Sainte Marguerite, Marseille, 13009, France.
  • Dusetti N; Hôpital de la Timone, 264 rue Saint-Pierre, Marseille, 13385, France.
  • Iovanna J; Hôpital Nord, Chemin des Bourrely, Marseille, 13015, France.
  • Urrutia R; Hôpital Nord, Chemin des Bourrely, Marseille, 13015, France.
Nat Commun ; 9(1): 1978, 2018 05 17.
Article em En | MEDLINE | ID: mdl-29773832
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Carcinoma Ductal Pancreático / Epigênese Genética Tipo de estudo: Prognostic_studies Limite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Carcinoma Ductal Pancreático / Epigênese Genética Tipo de estudo: Prognostic_studies Limite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos