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Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.
Readhead, Ben; Haure-Mirande, Jean-Vianney; Funk, Cory C; Richards, Matthew A; Shannon, Paul; Haroutunian, Vahram; Sano, Mary; Liang, Winnie S; Beckmann, Noam D; Price, Nathan D; Reiman, Eric M; Schadt, Eric E; Ehrlich, Michelle E; Gandy, Sam; Dudley, Joel T.
Afiliação
  • Readhead B; Departments of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Institute for Next Generation Healthcare, Icahn School of Medi
  • Haure-Mirande JV; Department of Neurology, Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Funk CC; Institute for Systems Biology, Seattle, WA, 98109-5263, USA.
  • Richards MA; Institute for Systems Biology, Seattle, WA, 98109-5263, USA.
  • Shannon P; Institute for Systems Biology, Seattle, WA, 98109-5263, USA.
  • Haroutunian V; Departments of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; James J. Peters VA Medical Center, 130 West Kingsbridge Road, New York, NY 10468, USA.
  • Sano M; James J. Peters VA Medical Center, 130 West Kingsbridge Road, New York, NY 10468, USA; Department of Psychiatry, Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Liang WS; Arizona Alzheimer's Consortium, Phoenix, AZ 85014, USA; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA.
  • Beckmann ND; Departments of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Price ND; Institute for Systems Biology, Seattle, WA, 98109-5263, USA.
  • Reiman EM; Arizona Alzheimer's Consortium, Phoenix, AZ 85014, USA; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ 85004, USA; Department of Psychiatry, University of Arizona, Phoenix, AZ 85721, USA; Banner Alzheimer's Institute, Phoenix, AZ 85006, USA.
  • Schadt EE; Departments of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Sema4, Stamford, CT 06902, USA.
  • Ehrlich ME; Departments of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Neurology, Alzheimer's Disease Research Center,
  • Gandy S; Department of Neurology, Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; James J. Peters VA Medical Center, 130 West Kingsbridge Road, New York, NY 10468, USA; Department of Psychiatry, Alzheimer's Disease Research Center, Icahn School of Medici
  • Dudley JT; Departments of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Institute for Next Generation Healthcare, Icahn School of Medi
Neuron ; 99(1): 64-82.e7, 2018 07 11.
Article em En | MEDLINE | ID: mdl-29937276
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_alzheimer_other_dementias / 6_mental_health_behavioral_disorders Assunto principal: Encéfalo / Precursor de Proteína beta-Amiloide / Herpesvirus Humano 6 / Herpesvirus Humano 7 / Encefalite Viral / Infecções por Roseolovirus / Doença de Alzheimer Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_alzheimer_other_dementias / 6_mental_health_behavioral_disorders Assunto principal: Encéfalo / Precursor de Proteína beta-Amiloide / Herpesvirus Humano 6 / Herpesvirus Humano 7 / Encefalite Viral / Infecções por Roseolovirus / Doença de Alzheimer Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2018 Tipo de documento: Article