Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1.

Trinh, Michael Nguyen; Brown, Michael S; Seemann, Joachim; Goldstein, Joseph L; Lu, Feiran

Trinh, Michael Nguyen; Brown, Michael S; Seemann, Joachim; Goldstein, Joseph L; Lu, Feiran.

Afiliação

Trinh MN; Departments of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States.
Brown MS; Departments of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States.
Seemann J; Cell Biology, University of Texas Southwestern Medical Center, Dallas, United States.
Goldstein JL; Departments of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States.
Lu F; Departments of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United States.

Elife ; 72018 07 26.

Article em En | MEDLINE | ID: mdl-30047864

Assuntos

Transporte Biológico/genética; Colesterol/química; Bicamadas Lipídicas/química; Proteína C1 de Niemann-Pick/química; Animais; Sítios de Ligação; Células CHO; Colesterol/genética; Cricetinae; Cricetulus; Glicocálix/química; Humanos; Lisossomos/química; Lisossomos/genética; Proteína C1 de Niemann-Pick/genética

Palavras-chave

NPC1 fragments; biochemistry; cell biology; chemical biology; cholesterol transport; human; lysosome; reconstitution; split nanoluciferase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transporte Biológico / Colesterol / Proteína C1 de Niemann-Pick / Bicamadas Lipídicas Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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