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Progress in studies of necroptosis and its relationship to disease processes.
Wang, Zhen; Guo, Li-Min; Wang, Shu-Chao; Chen, Dan; Yan, Jie; Liu, Feng-Xia; Huang, Ju-Fang; Xiong, Kun.
Afiliação
  • Wang Z; Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, 214122, China.
  • Guo LM; Department of Neurobiology and Human Anatomy, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China.
  • Wang SC; Department of Neurobiology and Human Anatomy, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China.
  • Chen D; Department of Neurobiology and Human Anatomy, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China.
  • Yan J; Department of Forensic Science, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China.
  • Liu FX; Department of Human Anatomy, School of Basic Medical Science, Xinjiang Medical University, Urumqi, Xinjiang, 830011, China.
  • Huang JF; Department of Neurobiology and Human Anatomy, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China. Electronic address: huangjufang@csu.edu.cn.
  • Xiong K; Department of Neurobiology and Human Anatomy, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China. Electronic address: xiongkun2001@163.com.
Pathol Res Pract ; 214(11): 1749-1757, 2018 Nov.
Article em En | MEDLINE | ID: mdl-30244947
ABSTRACT
This review briefly introduces the mechanism and detection methods of necroptosis in recent years. The most significant points of this review focus on the involvement of necroptotic proteins in disease progression. The following aspects are summarized 1) RIPs, MLKL, and the upstream and downstream molecules that mediate necroptosis; 2) The development of detection methods for necroptosis; 3) The involvement of related necroptotic proteins in diverse diseases etiology; and 4) The application of necroptotic proteins in disease diagnosis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Morte Celular Limite: Animals / Humans Idioma: En Revista: Pathol Res Pract Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Morte Celular Limite: Animals / Humans Idioma: En Revista: Pathol Res Pract Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
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