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Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aß and TAU proteostasis.
Sullivan, Sarah E; Liao, Meichen; Smith, Robert V; White, Charles; Lagomarsino, Valentina N; Xu, Jishu; Taga, Mariko; Bennett, David A; De Jager, Philip L; Young-Pearse, Tracy L.
Afiliação
  • Sullivan SE; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Liao M; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Smith RV; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • White C; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.
  • Lagomarsino VN; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Xu J; Cell Circuits Program, Broad Institute, Cambridge, MA, USA.
  • Taga M; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.
  • Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
  • De Jager PL; Cell Circuits Program, Broad Institute, Cambridge, MA, USA.
  • Young-Pearse TL; Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.
Hum Mol Genet ; 28(5): 718-735, 2019 03 01.
Article em En | MEDLINE | ID: mdl-30371777
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Astrócitos / Peptídeos beta-Amiloides / Proteínas tau / Proteostase / Proteínas de Membrana / Proteínas de Neoplasias / Neurônios Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Astrócitos / Peptídeos beta-Amiloides / Proteínas tau / Proteostase / Proteínas de Membrana / Proteínas de Neoplasias / Neurônios Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos