ISL1 loss-of-function mutation contributes to congenital heart defects.

Ma, Lan; Wang, Juan; Li, Li; Qiao, Qi; Di, Ruo-Min; Li, Xiu-Mei; Xu, Ying-Jia; Zhang, Min; Li, Ruo-Gu; Qiu, Xing-Biao; Li, Xun; Yang, Yi-Qing

Ma, Lan; Wang, Juan; Li, Li; Qiao, Qi; Di, Ruo-Min; Li, Xiu-Mei; Xu, Ying-Jia; Zhang, Min; Li, Ruo-Gu; Qiu, Xing-Biao; Li, Xun; Yang, Yi-Qing.

Afiliação

Ma L; Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
Wang J; Department of Ultrasound, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200030, China.
Li L; Department of Cardiovascular Medicine, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Qiao Q; Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Di RM; Department of Cardiology, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Li XM; Department of Cardiology, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Xu YJ; Department of Cardiology, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Zhang M; Department of Cardiology, The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, 200240, China.
Li RG; Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200030, China.
Qiu XB; Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200030, China.
Li X; Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200030, China.
Yang YQ; Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China. xunli58@126.com.

Heart Vessels ; 34(4): 658-668, 2019 Apr.

Article em En | MEDLINE | ID: mdl-30390123

Assuntos

DNA/genética; Cardiopatias Congênitas/genética; Proteínas com Homeodomínio LIM/genética; Mutação com Perda de Função; Fatores de Transcrição/genética; Adolescente; Adulto; Criança; Pré-Escolar; Análise Mutacional de DNA; Éxons; Feminino; Cardiopatias Congênitas/metabolismo; Humanos; Lactente; Proteínas com Homeodomínio LIM/metabolismo; Masculino; Linhagem; Reação em Cadeia da Polimerase; Fatores de Transcrição/metabolismo; Adulto Jovem

Palavras-chave

Congenital heart defect; ISL1; Molecular genetics; Patent ductus arteriosus; Reporter gene assay; Transcription factor

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles / 7_ODS3_muertes_prevenibles_nacidos_ninos Problema de saúde: 2_muertes_prevenibles / 6_cardiovascular_diseases / 6_congenital_chromosomal_anomalies / 6_other_circulatory_diseases / 7_neonatal_care_health / 7_non_communicable_diseases Assunto principal: Fatores de Transcrição / DNA / Proteínas com Homeodomínio LIM / Mutação com Perda de Função / Cardiopatias Congênitas Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Heart Vessels Assunto da revista: CARDIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google