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Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome.
Kozikowski, Alan P; Shen, Sida; Pardo, Marta; Tavares, Maurício T; Szarics, Dora; Benoy, Veronick; Zimprich, Chad A; Kutil, Zsófia; Zhang, Guiping; Barinka, Cyril; Robers, Matthew B; Van Den Bosch, Ludo; Eubanks, James H; Jope, Richard S.
Afiliação
  • Kozikowski AP; StarWise Therapeutics LLC , Madison , Wisconsin 53719 , United States.
  • Shen S; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy , University of Illinois at Chicago , Chicago , Illinois 60612 , United States.
  • Pardo M; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine , University of Miami , Miami , Florida 33136 , United States.
  • Tavares MT; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy , University of Illinois at Chicago , Chicago , Illinois 60612 , United States.
  • Szarics D; Division of Genetics and Development, Krembil Research Institute , University Health Network , Toronto , Ontario M5G 2C4 , Canada.
  • Benoy V; Laboratory of Neurobiology, Center for Brain & Disease (VIB) and Leuven Brain Institute (LBI) , KU Leuven , B-3000 Leuven , Belgium.
  • Zimprich CA; Promega Corporation , Madison , Wisconsin 53711 , United States.
  • Kutil Z; Laboratory of Structural Biology , Institute of Biotechnology of the Czech Academy of Sciences , Prumyslova 595 , 252 50 Vestec , Czech Republic.
  • Zhang G; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy , University of Illinois at Chicago , Chicago , Illinois 60612 , United States.
  • Barinka C; Laboratory of Structural Biology , Institute of Biotechnology of the Czech Academy of Sciences , Prumyslova 595 , 252 50 Vestec , Czech Republic.
  • Robers MB; Promega Corporation , Madison , Wisconsin 53711 , United States.
  • Van Den Bosch L; Laboratory of Neurobiology, Center for Brain & Disease (VIB) and Leuven Brain Institute (LBI) , KU Leuven , B-3000 Leuven , Belgium.
  • Eubanks JH; Division of Genetics and Development, Krembil Research Institute , University Health Network , Toronto , Ontario M5G 2C4 , Canada.
  • Jope RS; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine , University of Miami , Miami , Florida 33136 , United States.
ACS Chem Neurosci ; 10(3): 1679-1695, 2019 03 20.
Article em En | MEDLINE | ID: mdl-30511829
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Benzamidas / Inibidores de Histona Desacetilases / Desacetilase 6 de Histona / Síndrome do Cromossomo X Frágil / Aprendizagem / Memória Limite: Animals Idioma: En Revista: ACS Chem Neurosci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Benzamidas / Inibidores de Histona Desacetilases / Desacetilase 6 de Histona / Síndrome do Cromossomo X Frágil / Aprendizagem / Memória Limite: Animals Idioma: En Revista: ACS Chem Neurosci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos