Development of XIAP Antagonists Based On De Novo 8,5-Fused Bicyclic Lactams.

Sheng, Zhaojun J; Shi, Yiming M; Xu, Ximing; Bellynck, Sébastien; Zhang, Kun; Du, Zhiyun Y; Xu, Xuetao; Maurel, François; Dong, Chang-Zhi

Sheng, Zhaojun J; Shi, Yiming M; Xu, Ximing; Bellynck, Sébastien; Zhang, Kun; Du, Zhiyun Y; Xu, Xuetao; Maurel, François; Dong, Chang-Zhi.

Afiliação

Sheng ZJ; Interfaces, Traitements, Organisation et Dynamique des Systemes (ITODYS) UMR 7086 CNRS Université Paris Diderot, Sorbonne Paris Cité 75205 Paris France.
Shi YM; School of Chemical Engineering and Light Industry Institute of Natural Medicine and Green Chemistry Guangdong University of Technology 510006 Guangzhou China.
Xu X; School of Chemical and Environment Engineering Wuyi University 529020 Jiangmen China.
Bellynck S; Interfaces, Traitements, Organisation et Dynamique des Systemes (ITODYS) UMR 7086 CNRS Université Paris Diderot, Sorbonne Paris Cité 75205 Paris France.
Zhang K; School of Electrical and Information Engineering Institute of Bioinformatics and Medical Engineering Jiangsu University of Technology 213001 Changzhou China.
Du ZY; Interfaces, Traitements, Organisation et Dynamique des Systemes (ITODYS) UMR 7086 CNRS Université Paris Diderot, Sorbonne Paris Cité 75205 Paris France.
Xu X; School of Chemical Engineering and Light Industry Institute of Natural Medicine and Green Chemistry Guangdong University of Technology 510006 Guangzhou China.
Maurel F; School of Chemical and Environment Engineering Wuyi University 529020 Jiangmen China.
Dong CZ; School of Chemical Engineering and Light Industry Institute of Natural Medicine and Green Chemistry Guangdong University of Technology 510006 Guangzhou China.

ChemistryOpen ; 8(1): 34-40, 2019 Jan.

Article em En | MEDLINE | ID: mdl-30652062

Palavras-chave

Smac mimetics; XIAP antagonists; anticancer drugs; lactams; spontaneous rearrangement

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ChemistryOpen Ano de publicação: 2019 Tipo de documento: Article