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Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment.
Brial, Francois; Le Lay, Aurélie; Hedjazi, Lyamine; Tsang, Tsz; Fearnside, Jane F; Otto, Georg W; Alzaid, Fawaz; Wilder, Steven P; Venteclef, Nicolas; Cazier, Jean-Baptiste; Nicholson, Jeremy K; Day, Chris; Burt, Alastair D; Gut, Ivo G; Lathrop, Mark; Dumas, Marc-Emmanuel; Gauguier, Dominique.
Afiliação
  • Brial F; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France.
  • Le Lay A; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France.
  • Hedjazi L; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France.
  • Tsang T; Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, United Kingdom.
  • Fearnside JF; School of Health and Related Research, The University of Sheffield, 30 Regent Court, Sheffield, S10 2TA, United Kingdom.
  • Otto GW; Genetics and Genomic Medicine, University College London Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, United Kingdom.
  • Alzaid F; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France.
  • Wilder SP; The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, OX3 7BN, United Kingdom.
  • Venteclef N; Genomics Plc, King Charles House, Oxford, Park End Street, OX1 1JD, United Kingdom.
  • Cazier JB; Sorbonne University, University Paris Descartes, University Paris Diderot, INSERM UMR_S 1138, Cordeliers Research Centre, 75006, Paris, France.
  • Nicholson JK; Centre for Computational Biology, Medical School, University of Birmingham, Birmingham, B15 2TT, United Kingdom.
  • Day C; Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, United Kingdom.
  • Burt AD; The Australian National Phenome Centre, Murdoch University, Perth, WA6150, Australia.
  • Gut IG; Faculty of Medical Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, United Kingdom.
  • Lathrop M; Faculty of Medical Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, United Kingdom.
  • Dumas ME; Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia.
  • Gauguier D; CNAG-CRG, Centre for Genomic Regulation, Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 4, 08028, Barcelona, Spain.
Sci Rep ; 9(1): 3656, 2019 03 06.
Article em En | MEDLINE | ID: mdl-30842494
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Octopamina / Polimorfismo de Nucleotídeo Único / Cromossomos de Mamíferos / Metabolômica / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: França
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Octopamina / Polimorfismo de Nucleotídeo Único / Cromossomos de Mamíferos / Metabolômica / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: França