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The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aß Plaques.
Sala Frigerio, Carlo; Wolfs, Leen; Fattorelli, Nicola; Thrupp, Nicola; Voytyuk, Iryna; Schmidt, Inga; Mancuso, Renzo; Chen, Wei-Ting; Woodbury, Maya E; Srivastava, Gyan; Möller, Thomas; Hudry, Eloise; Das, Sudeshna; Saido, Takaomi; Karran, Eric; Hyman, Bradley; Perry, V Hugh; Fiers, Mark; De Strooper, Bart.
Afiliação
  • Sala Frigerio C; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium; UK Dementia Research Institute, University College London, London, UK. Electronic address: carlo.salafrigerio@kuleuven.vib.be.
  • Wolfs L; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium.
  • Fattorelli N; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium.
  • Thrupp N; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium.
  • Voytyuk I; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium.
  • Schmidt I; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium.
  • Mancuso R; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium.
  • Chen WT; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium.
  • Woodbury ME; Foundational Neuroscience Center, AbbVie, Inc., Cambridge, MA, USA.
  • Srivastava G; Foundational Neuroscience Center, AbbVie, Inc., Cambridge, MA, USA.
  • Möller T; Foundational Neuroscience Center, AbbVie, Inc., Cambridge, MA, USA.
  • Hudry E; Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
  • Das S; Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
  • Saido T; Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako-shi, Saitama, Japan.
  • Karran E; Foundational Neuroscience Center, AbbVie, Inc., Cambridge, MA, USA.
  • Hyman B; Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
  • Perry VH; UK Dementia Research Institute, University College London, London, UK; Centre for Biological Sciences, University of Southampton, Southampton, UK.
  • Fiers M; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium.
  • De Strooper B; VIB Centre for Brain Disease Research, Leuven, Belgium; University of Leuven, Department of Neurosciences and Leuven Brain Institute, Leuven, Belgium; UK Dementia Research Institute, University College London, London, UK. Electronic address: bart.destrooper@kuleuven.vib.be.
Cell Rep ; 27(4): 1293-1306.e6, 2019 04 23.
Article em En | MEDLINE | ID: mdl-31018141
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Envelhecimento / Biomarcadores / Microglia / Placa Amiloide / Modelos Animais de Doenças / Doença de Alzheimer Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Envelhecimento / Biomarcadores / Microglia / Placa Amiloide / Modelos Animais de Doenças / Doença de Alzheimer Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article