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Clinical pharmacokinetics and pharmacodynamics of ivosidenib, an oral, targeted inhibitor of mutant IDH1, in patients with advanced solid tumors.
Fan, Bin; Mellinghoff, Ingo K; Wen, Patrick Y; Lowery, Maeve A; Goyal, Lipika; Tap, William D; Pandya, Shuchi S; Manyak, Erika; Jiang, Liewen; Liu, Guowen; Nimkar, Tara; Gliser, Camelia; Prahl Judge, Molly; Agresta, Sam; Yang, Hua; Dai, David.
Afiliação
  • Fan B; DMPK, Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, MA, 02139, USA. bin.fan@agios.com.
  • Mellinghoff IK; Departments of Neurology and Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Wen PY; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Lowery MA; Trinity St James Cancer Institute, Trinity College, Dublin, Ireland.
  • Goyal L; Department of Internal Medicine, Division of Hematology/Oncology, Massachusetts General Hospital Cancer Center, Boston, MA, USA.
  • Tap WD; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Pandya SS; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
  • Manyak E; Clinical Development, Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Jiang L; DMPK, Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Liu G; Biostatistics - Clinical Development, Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Nimkar T; DMPK, Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, MA, 02139, USA.
  • Gliser C; Clinical Operations - Clinical Development, Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Prahl Judge M; Clinical Development, Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Agresta S; Clinical Development, Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Yang H; Clinical Development, Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Dai D; DMPK, Agios Pharmaceuticals, Inc., 88 Sidney Street, Cambridge, MA, 02139, USA.
Invest New Drugs ; 38(2): 433-444, 2020 04.
Article em En | MEDLINE | ID: mdl-31028664
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Glicina / Isocitrato Desidrogenase / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Glicina / Isocitrato Desidrogenase / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos