Alkylation Reactions of Azodicarboxylate Esters with 4-Alkyl-1,4-Dihydropyridines under Catalyst-Free Conditions.
Org Lett
; 21(12): 4642-4645, 2019 Jun 21.
Article
em En
| MEDLINE
| ID: mdl-31145630
ABSTRACT
Introduction of alkyl groups on azodicarboxylate esters is an important method to prepare alkyl amine derivatives. Herein, we report reactions of 4-alkyl-1,4-dihydropyridines as alkylation reagents with di- tert-butyl azodicarboxylate to prepare alkyl amine derivatives under heating conditions. The alkylation reactions via C-C bond cleavage of the dihydropyridines are achieved in the absence of catalysts and additives.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Japão