Your browser doesn't support javascript.
loading
State of Colon Microbiota in Rats during Chronic Restraint Stress and Selank Treatment.
Mukhina, A Yu; Medvedeva, O A; Svishcheva, M V; Shevchenko, A V; Efremova, N N; Bobyntsev, I I; Kalutskii, P V; Andreeva, L A; Myasoedov, N F.
Afiliação
  • Mukhina AY; Kursk State Medical University, Ministry of Health of the Russian Federation, Kursk, Russia.
  • Medvedeva OA; Kursk State Medical University, Ministry of Health of the Russian Federation, Kursk, Russia.
  • Svishcheva MV; Kursk State Medical University, Ministry of Health of the Russian Federation, Kursk, Russia.
  • Shevchenko AV; Kursk State Medical University, Ministry of Health of the Russian Federation, Kursk, Russia.
  • Efremova NN; Kursk State Medical University, Ministry of Health of the Russian Federation, Kursk, Russia.
  • Bobyntsev II; Kursk State Medical University, Ministry of Health of the Russian Federation, Kursk, Russia. bobig@mail.ru.
  • Kalutskii PV; Kursk State Medical University, Ministry of Health of the Russian Federation, Kursk, Russia.
  • Andreeva LA; Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia.
  • Myasoedov NF; Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia.
Bull Exp Biol Med ; 167(2): 226-228, 2019 Jun.
Article em En | MEDLINE | ID: mdl-31236882
ABSTRACT
We studied the effects of Selank on intestinal microbiota in Wistar male rats subjected to chronic restraint stress. Selank was injected intraperitoneally in doses of 80, 250 and 750 µg/kg 15 min before stress exposure. Chronic restraint stress led to a decrease in the content of obligate microflora, while the content of opportunistic microorganisms increased. Selank restored intestinal microbiota presumably via central (neurotropic) and peripheral (immunotropic) mechanisms.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 3_ND Problema de saúde: 3_zoonosis Assunto principal: Oligopeptídeos / Restrição Física / Colo / Microbioma Gastrointestinal Limite: Animals Idioma: En Revista: Bull Exp Biol Med Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Federação Russa
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 3_ND Problema de saúde: 3_zoonosis Assunto principal: Oligopeptídeos / Restrição Física / Colo / Microbioma Gastrointestinal Limite: Animals Idioma: En Revista: Bull Exp Biol Med Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Federação Russa