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The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice.
Debeuf, Nincy; Zhakupova, Assem; Steiner, Regula; Van Gassen, Sofie; Deswarte, Kim; Fayazpour, Farzaneh; Van Moorleghem, Justine; Vergote, Karl; Pavie, Benjamin; Lemeire, Kelly; Hammad, Hamida; Hornemann, Thorsten; Janssens, Sophie; Lambrecht, Bart N.
Afiliação
  • Debeuf N; Laboratory of Mucosal Immunology and Immunoregulation, VIB Center for Inflammation Research, Ghent, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Zhakupova A; Institute of Clinical Chemistry, University and University Hospital Zurich, Zurich, Switzerland.
  • Steiner R; Institute of Clinical Chemistry, University and University Hospital Zurich, Zurich, Switzerland.
  • Van Gassen S; Data Mining and Modeling for Biomedicine, VIB Center for Inflammation Research, Ghent, Belgium; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.
  • Deswarte K; Laboratory of Mucosal Immunology and Immunoregulation, VIB Center for Inflammation Research, Ghent, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Fayazpour F; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium; Laboratory for ER Stress and Inflammation, VIB Center for Inflammation Research, Ghent, Belgium.
  • Van Moorleghem J; Laboratory of Mucosal Immunology and Immunoregulation, VIB Center for Inflammation Research, Ghent, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Vergote K; Laboratory of Mucosal Immunology and Immunoregulation, VIB Center for Inflammation Research, Ghent, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Pavie B; VIB Bioimaging Core, VIB Center for Inflammation Research, Ghent, Belgium; Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Lemeire K; Biomedical Molecular Biology, Ghent University, Ghent, Belgium; VIB Center for Inflammation Research, Ghent, Belgium.
  • Hammad H; Laboratory of Mucosal Immunology and Immunoregulation, VIB Center for Inflammation Research, Ghent, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Hornemann T; Institute of Clinical Chemistry, University and University Hospital Zurich, Zurich, Switzerland.
  • Janssens S; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium; Laboratory for ER Stress and Inflammation, VIB Center for Inflammation Research, Ghent, Belgium.
  • Lambrecht BN; Laboratory of Mucosal Immunology and Immunoregulation, VIB Center for Inflammation Research, Ghent, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address: bar
J Allergy Clin Immunol ; 144(6): 1648-1659.e9, 2019 12.
Article em En | MEDLINE | ID: mdl-31330218
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Ceramidas / Células Th2 / Metabolismo dos Lipídeos / Proteínas de Membrana Limite: Animals Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Ceramidas / Células Th2 / Metabolismo dos Lipídeos / Proteínas de Membrana Limite: Animals Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica