European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND).
Alzheimers Dement (Amst)
; 11: 538-549, 2019 Dec.
Article
em En
| MEDLINE
| ID: mdl-31388558
ABSTRACT
INTRODUCTION:
The goal of European Ultrahigh-Field Imaging Network in Neurodegenerative Diseases (EUFIND) is to identify opportunities and challenges of 7 Tesla (7T) MRI for clinical and research applications in neurodegeneration. EUFIND comprises 22 European and one US site, including over 50 MRI and dementia experts as well as neuroscientists.METHODS:
EUFIND combined consensus workshops and data sharing for multisite analysis, focusing on 7 core topics clinical applications/clinical research, highest resolution anatomy, functional imaging, vascular systems/vascular pathology, iron mapping and neuropathology detection, spectroscopy, and quality assurance. Across these topics, EUFIND considered standard operating procedures, safety, and multivendor harmonization.RESULTS:
The clinical and research opportunities and challenges of 7T MRI in each subtopic are set out as a roadmap. Specific MRI sequences for each subtopic were implemented in a pilot study presented in this report. Results show that a large multisite 7T imaging network with highly advanced and harmonized imaging sequences is feasible and may enable future multicentre ultrahigh-field MRI studies and clinical trials.DISCUSSION:
The EUFIND network can be a major driver for advancing clinical neuroimaging research using 7T and for identifying use-cases for clinical applications in neurodegeneration.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Alzheimers Dement (Amst)
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Alemanha