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Safety and efficacy of pembrolizumab monotherapy in elderly patients with PD-L1-positive advanced non-small-cell lung cancer: Pooled analysis from the KEYNOTE-010, KEYNOTE-024, and KEYNOTE-042 studies.
Nosaki, Kaname; Saka, Hideo; Hosomi, Yukio; Baas, Paul; de Castro, Gilberto; Reck, Martin; Wu, Yi-Long; Brahmer, Julie R; Felip, Enriqueta; Sawada, Takeshi; Noguchi, Kazuo; Han, Shi Rong; Piperdi, Bilal; Kush, Debra A; Lopes, Gilberto.
Afiliação
  • Nosaki K; National Hospital Organization Kyushu Cancer Center, Minami-ku, Fukuoka-shi, Fukuoka 811-1395, Japan. Electronic address: knosaki@east.ncc.go.jp.
  • Saka H; National Hospital Organization Nagoya Medical Center, 4-1-1 Sannomaru, Naka-ku, Nagoya, Aichi 460-0001, Japan. Electronic address: hideosaka@me.com.
  • Hosomi Y; Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo 113-8677, Japan. Electronic address: yhosomi@cick.jp.
  • Baas P; The Netherlands Cancer Institute, Postbus 90203, 1006 BE Amsterdam, the Netherlands. Electronic address: p.baas@nki.nl.
  • de Castro G; Instituto do Câncer do Estado de São Paulo, Av. Dr. Arnaldo, 251 - Cerqueira César, São Paulo, SP 01246-000, Brazil. Electronic address: gilberto.castro@usp.br.
  • Reck M; Lung Clinic Grosshansdorf, Airway Research Center North (ARCN), member of the German Center for Lung Research (DZL), Wöhrendamm 80, 22927 Grosshansdorf, Germany. Electronic address: M.Reck@lungenclinic.de.
  • Wu YL; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, and Guangdong Academy of Medical Sciences, Guangdong, 106 Zhongshan 2nd Rd, Yuexiu Qu, Guangzhou Shi, Guangdong Sheng 510080, China. Electronic address: syylwu@live.cn.
  • Brahmer JR; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans St, Baltimore, 21287 MD, USA. Electronic address: brahmju@jhmi.edu.
  • Felip E; Vall d'Hebron University Hospital, P. Vall d'Hebron, 119-129, 08035 and IOB Quiron, Barcelona, Spain. Electronic address: efelip@vhio.net.
  • Sawada T; MSD K.K., Kitanomaru Square, 1-13-12, Kudan Kita, Chiyoda-ku, Tokyo 102-8667, Japan. Electronic address: takeshi.sawada@merck.com.
  • Noguchi K; MSD K.K., Kitanomaru Square, 1-13-12, Kudan Kita, Chiyoda-ku, Tokyo 102-8667, Japan. Electronic address: kazuo.noguchi@merck.com.
  • Han SR; MSD K.K., Kitanomaru Square, 1-13-12, Kudan Kita, Chiyoda-ku, Tokyo 102-8667, Japan. Electronic address: shi.rong.han@merck.com.
  • Piperdi B; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA. Electronic address: bilal.piperdi@merck.com.
  • Kush DA; Merck & Co., Inc., 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA. Electronic address: debra_kush@merck.com.
  • Lopes G; Sylvester Comprehensive Cancer Center at the University of Miami, 1475 NW 12th Ave, Miami, FL 33136, USA. Electronic address: glopes.md@gmail.com.
Lung Cancer ; 135: 188-195, 2019 09.
Article em En | MEDLINE | ID: mdl-31446994
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_other_respiratory_diseases / 6_trachea_bronchus_lung_cancer Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Anticorpos Monoclonais Humanizados / Antígeno B7-H1 / Antineoplásicos Imunológicos / Neoplasias Pulmonares Tipo de estudo: Clinical_trials / Diagnostic_studies / Systematic_reviews Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Lung Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_other_respiratory_diseases / 6_trachea_bronchus_lung_cancer Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Anticorpos Monoclonais Humanizados / Antígeno B7-H1 / Antineoplásicos Imunológicos / Neoplasias Pulmonares Tipo de estudo: Clinical_trials / Diagnostic_studies / Systematic_reviews Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Lung Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article