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Atp6ap2 deletion causes extensive vacuolation that consumes the insulin content of pancreatic ß cells.
Binger, Katrina J; Neukam, Martin; Tattikota, Sudhir Gopal; Qadri, Fatimunnisa; Puchkov, Dmytro; Willmes, Diana M; Wurmsee, Sabrina; Geisberger, Sabrina; Dechend, Ralf; Raile, Klemens; Kurth, Thomas; Nguyen, Genevieve; Poy, Matthew N; Solimena, Michele; Muller, Dominik N; Birkenfeld, Andreas L.
Afiliação
  • Binger KJ; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia; k.binger@latrobe.edu.au.
  • Neukam M; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia.
  • Tattikota SG; Molecular Diabetology, Paul Langerhans Institute Dresden (PLID) of the Helmholtz German Center for Diabetes Research (DZD e.V.) Munich, University Hospital Carl Gustav Carus and Faculty of Medicine, TU Dresden, 01307 Dresden, Germany.
  • Qadri F; Department of Genetics, Harvard Medical School, Boston, MA 02115.
  • Puchkov D; Cardiovascular and Metabolic Diseases, Max Delbruck Center (MDC) for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.
  • Willmes DM; Cardiovascular and Metabolic Diseases, Max Delbruck Center (MDC) for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.
  • Wurmsee S; Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin and Max Delbruck Center for Molecular Medicine, 13125 Berlin, Germany.
  • Geisberger S; Cellular Imaging Facility, Leibniz Institute for Molecular Pharmacology (FMP) Berlin, 13125 Berlin, Germany.
  • Dechend R; Molecular Diabetology, Paul Langerhans Institute Dresden (PLID) of the Helmholtz German Center for Diabetes Research (DZD e.V.) Munich, University Hospital Carl Gustav Carus and Faculty of Medicine, TU Dresden, 01307 Dresden, Germany.
  • Raile K; Cardiovascular and Metabolic Diseases, Max Delbruck Center (MDC) for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.
  • Kurth T; Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin and Max Delbruck Center for Molecular Medicine, 13125 Berlin, Germany.
  • Nguyen G; Cardiovascular and Metabolic Diseases, Max Delbruck Center (MDC) for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany.
  • Poy MN; Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin and Max Delbruck Center for Molecular Medicine, 13125 Berlin, Germany.
  • Solimena M; Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin and Max Delbruck Center for Molecular Medicine, 13125 Berlin, Germany.
  • Muller DN; Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin and Max Delbruck Center for Molecular Medicine, 13125 Berlin, Germany.
  • Birkenfeld AL; Center for Molecular and Cellular Bioengineering, Center for Regenerative Therapies Dresden, TU Dresden, 01307 Dresden, Germany.
Proc Natl Acad Sci U S A ; 116(40): 19983-19988, 2019 10 01.
Article em En | MEDLINE | ID: mdl-31527264

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deleção de Genes / ATPases Translocadoras de Prótons / Receptores de Superfície Celular / Células Secretoras de Insulina / Insulina Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deleção de Genes / ATPases Translocadoras de Prótons / Receptores de Superfície Celular / Células Secretoras de Insulina / Insulina Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article
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