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Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity.
Kouba, Sana; Braire, Julien; Félix, Romain; Chantôme, Aurélie; Jaffrès, Paul-Alain; Lebreton, Jacques; Dubreuil, Didier; Pipelier, Muriel; Zhang, Xuexin; Trebak, Mohamed; Vandier, Christophe; Mathé-Allainmat, Monique; Potier-Cartereau, Marie.
Afiliação
  • Kouba S; University of Tours, Inserm U1069 Nutrition, Croissance et Cancer (N2C), Faculty of Medicine, 10 Boulevard Tonnellé, 37032, Tours Cedex, France.
  • Braire J; University of Nantes, CNRS, Faculty of Sciences, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, 2, Rue de La Houssinière, 44322, Nantes Cedex 3, France.
  • Félix R; University of Tours, Inserm U1069 Nutrition, Croissance et Cancer (N2C), Faculty of Medicine, 10 Boulevard Tonnellé, 37032, Tours Cedex, France.
  • Chantôme A; University of Tours, Inserm U1069 Nutrition, Croissance et Cancer (N2C), Faculty of Medicine, 10 Boulevard Tonnellé, 37032, Tours Cedex, France.
  • Jaffrès PA; University of Brest, CNRS, CEMCA, UMR 6521, 6 Avenue Victor Le Gorgeu, 29238, Brest, France.
  • Lebreton J; University of Nantes, CNRS, Faculty of Sciences, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, 2, Rue de La Houssinière, 44322, Nantes Cedex 3, France.
  • Dubreuil D; University of Nantes, CNRS, Faculty of Sciences, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, 2, Rue de La Houssinière, 44322, Nantes Cedex 3, France.
  • Pipelier M; University of Nantes, CNRS, Faculty of Sciences, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, 2, Rue de La Houssinière, 44322, Nantes Cedex 3, France.
  • Zhang X; Pennylvania State University College of Medicine, Department of Cellular and Molecular Physiology, 700 HMC Crescent Road, Hershey, PA, 17033, USA.
  • Trebak M; Pennylvania State University College of Medicine, Department of Cellular and Molecular Physiology, 700 HMC Crescent Road, Hershey, PA, 17033, USA.
  • Vandier C; University of Tours, Inserm U1069 Nutrition, Croissance et Cancer (N2C), Faculty of Medicine, 10 Boulevard Tonnellé, 37032, Tours Cedex, France.
  • Mathé-Allainmat M; University of Nantes, CNRS, Faculty of Sciences, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, 2, Rue de La Houssinière, 44322, Nantes Cedex 3, France. Electronic address: monique.mathe@univ-nantes.fr.
  • Potier-Cartereau M; University of Tours, Inserm U1069 Nutrition, Croissance et Cancer (N2C), Faculty of Medicine, 10 Boulevard Tonnellé, 37032, Tours Cedex, France. Electronic address: marie.potier-cartereau@univ-tours.fr.
Eur J Med Chem ; 186: 111854, 2020 Jan 15.
Article em En | MEDLINE | ID: mdl-31753515
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Alcaloides / Canais de Potássio Ativados por Cálcio de Condutância Baixa / Lipídeos / Antineoplásicos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Alcaloides / Canais de Potássio Ativados por Cálcio de Condutância Baixa / Lipídeos / Antineoplásicos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: França