The impaired redox balance in peroxisomes of catalase knockout mice accelerates nonalcoholic fatty liver disease through endoplasmic reticulum stress.

Hwang, Inah; Uddin, Md Jamal; Pak, Eun Seon; Kang, Hyeji; Jin, Eun-Jung; Jo, Suin; Kang, Dongmin; Lee, Hyukjin; Ha, Hunjoo

Hwang, Inah; Uddin, Md Jamal; Pak, Eun Seon; Kang, Hyeji; Jin, Eun-Jung; Jo, Suin; Kang, Dongmin; Lee, Hyukjin; Ha, Hunjoo.

Afiliação

Hwang I; Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea.
Uddin MJ; Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea.
Pak ES; Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea.
Kang H; Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea.
Jin EJ; Department of Biological Sciences, College of Natural Sciences, Wonkwang University, Iksan, Chunbuk, 54538, Republic of Korea.
Jo S; Department of Life Science, Ewha Womans University, Seoul, 03760, Republic of Korea.
Kang D; Department of Life Science, Ewha Womans University, Seoul, 03760, Republic of Korea.
Lee H; Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea.
Ha H; Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea. Electronic address: hha@ewha.ac.kr.

Free Radic Biol Med ; 148: 22-32, 2020 02 20.

Article em En | MEDLINE | ID: mdl-31877356

Assuntos

Hepatopatia Gordurosa não Alcoólica; Animais; Catalase/genética; Catalase/metabolismo; Estresse do Retículo Endoplasmático; Peróxido de Hidrogênio/metabolismo; Fígado/metabolismo; Camundongos; Camundongos Knockout; Hepatopatia Gordurosa não Alcoólica/genética; Hepatopatia Gordurosa não Alcoólica/metabolismo; Oxirredução; Estresse Oxidativo; Peroxissomos/metabolismo

Palavras-chave

Catalase; ER stress; Hepatocytes; Nonalcoholic steatohepatitis; Peroxisomal biogenesis; Primary cell cultures; Reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Limite: Animals Idioma: En Revista: Free Radic Biol Med Assunto da revista: BIOQUIMICA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article

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