Iron-catalyzed stereospecific arylation of enol tosylates using Grignard reagents.
Chem Commun (Camb)
; 56(7): 1101-1104, 2020 Jan 23.
Article
em En
| MEDLINE
| ID: mdl-31894773
ABSTRACT
The stereospecific Fe-catalyzed arylation of enol tosylates was reported. Various tri- or tetrasubstituted Z or E-enol tosylates of ß-keto esters were arylated using common and Knochel-type Grignard reagents with complete stereofidelity. The precursors for Z/E-zimelidine, tamoxifen and other bioactive compounds were facilely prepared without precious and toxic transition metals.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Chem Commun (Camb)
Assunto da revista:
QUIMICA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China