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Leptomeningeal disease in melanoma patients: An update to treatment, challenges, and future directions.
Glitza, Isabella C; Smalley, Keiran S M; Brastianos, Priscilla K; Davies, Michael A; McCutcheon, Ian; Liu, James K C; Ahmed, Kamran A; Arrington, John A; Evernden, Brittany R; Smalley, Inna; Eroglu, Zeynep; Khushalani, Nikhil; Margolin, Kim; Kluger, Harriet; Atkins, Michael B; Tawbi, Hussein; Boire, Adrienne; Forsyth, Peter.
Afiliação
  • Glitza IC; Department of Melanoma Medical Oncology, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Smalley KSM; Melanoma Research Center of Excellence, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Brastianos PK; Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA.
  • Davies MA; Department of Melanoma Medical Oncology, UT MD Anderson Cancer Center, Houston, TX, USA.
  • McCutcheon I; Department of Neurosurgery, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Liu JKC; Department of Neuro-Oncology & Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Ahmed KA; Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Arrington JA; Head of Neuroradiology Section, Department of Radiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Evernden BR; Department of Neuro-Oncology & Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Smalley I; Department of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Eroglu Z; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Khushalani N; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Margolin K; Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA.
  • Kluger H; Department of Medical Oncology, Yale Cancer Center, New Haven, CT, USA.
  • Atkins MB; Department of Medical Oncology, Georgetown University Medical Center, Washington, DC, USA.
  • Tawbi H; Department of Melanoma Medical Oncology, UT MD Anderson Cancer Center, Houston, TX, USA.
  • Boire A; Department of Neuro-Oncology, Memorial Sloan Kettering, New York, NY, USA.
  • Forsyth P; Department of Neuro-Oncology & Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Pigment Cell Melanoma Res ; 33(4): 527-541, 2020 07.
Article em En | MEDLINE | ID: mdl-31916400
ABSTRACT
In February 2018, the Melanoma Research Foundation and the Moffitt Cancer Center hosted the Second Summit on Melanoma Central Nervous System Metastases in Tampa, Florida. The meeting included investigators from multiple academic centers and disciplines. A consensus summary of the progress and challenges in melanoma parenchymal brain metastases was published (Eroglu et al., Pigment Cell & Melanoma Research, 2019, 32, 458). Here, we will describe the current state of basic, translational, clinical research, and therapeutic management, for melanoma patients with leptomeningeal disease. We also outline key challenges and barriers to be overcome to make progress in this deadly disease.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Melanoma / Neoplasias Meníngeas Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Pigment Cell Melanoma Res Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Melanoma / Neoplasias Meníngeas Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Pigment Cell Melanoma Res Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
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