Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1&#945;.

Martin, Praxedis; Palmer, Gaby; Rodriguez, Emiliana; Palomo, Jennifer; Lemeille, Sylvain; Goldstein, Jérémie; Gabay, Cem

Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α.

Martin, Praxedis; Palmer, Gaby; Rodriguez, Emiliana; Palomo, Jennifer; Lemeille, Sylvain; Goldstein, Jérémie; Gabay, Cem.

Afiliação

Martin P; Department of Pathology and Immunology, School of Medicine, University of Geneva, 1211 Geneva 4, Switzerland; and.
Palmer G; Division of Rheumatology, Department of Internal Medicine Specialties, University Hospitals, 1211 Geneva 4, Switzerland.
Rodriguez E; Department of Pathology and Immunology, School of Medicine, University of Geneva, 1211 Geneva 4, Switzerland; and.
Palomo J; Division of Rheumatology, Department of Internal Medicine Specialties, University Hospitals, 1211 Geneva 4, Switzerland.
Lemeille S; Department of Pathology and Immunology, School of Medicine, University of Geneva, 1211 Geneva 4, Switzerland; and.
Goldstein J; Division of Rheumatology, Department of Internal Medicine Specialties, University Hospitals, 1211 Geneva 4, Switzerland.
Gabay C; Department of Pathology and Immunology, School of Medicine, University of Geneva, 1211 Geneva 4, Switzerland; and.

J Immunol ; 204(4): 967-979, 2020 02 15.

Article em En | MEDLINE | ID: mdl-31932497

Assuntos

Alarminas/antagonistas & inibidores; Apoptose/imunologia; Proteína Antagonista do Receptor de Interleucina 1/metabolismo; Interleucina-1alfa/antagonistas & inibidores; Psoríase/imunologia; Alarminas/imunologia; Alarminas/metabolismo; Animais; Modelos Animais de Doenças; Feminino; Humanos; Imiquimode/imunologia; Proteína Antagonista do Receptor de Interleucina 1/imunologia; Interleucina-1alfa/imunologia; Interleucina-1alfa/metabolismo; Queratinócitos/metabolismo; Masculino; Camundongos; Camundongos Knockout; Isoformas de Proteínas/imunologia; Isoformas de Proteínas/metabolismo; Psoríase/diagnóstico; Psoríase/patologia; Índice de Gravidade de Doença; Transdução de Sinais/imunologia; Pele/citologia; Pele/imunologia; Pele/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Problema de saúde: 6_skin_diseases Assunto principal: Psoríase / Apoptose / Proteína Antagonista do Receptor de Interleucina 1 / Interleucina-1alfa / Alarminas Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Immunol Ano de publicação: 2020 Tipo de documento: Article

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