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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle.
Favuzza, Paola; de Lera Ruiz, Manuel; Thompson, Jennifer K; Triglia, Tony; Ngo, Anna; Steel, Ryan W J; Vavrek, Marissa; Christensen, Janni; Healer, Julie; Boyce, Christopher; Guo, Zhuyan; Hu, Mengwei; Khan, Tanweer; Murgolo, Nicholas; Zhao, Lianyun; Penington, Jocelyn Sietsma; Reaksudsan, Kitsanapong; Jarman, Kate; Dietrich, Melanie H; Richardson, Lachlan; Guo, Kai-Yuan; Lopaticki, Sash; Tham, Wai-Hong; Rottmann, Matthias; Papenfuss, Tony; Robbins, Jonathan A; Boddey, Justin A; Sleebs, Brad E; Sabroux, Hélène Jousset; McCauley, John A; Olsen, David B; Cowman, Alan F.
Afiliação
  • Favuzza P; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • de Lera Ruiz M; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Thompson JK; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Triglia T; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Ngo A; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Steel RWJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Vavrek M; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Christensen J; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Healer J; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Boyce C; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Guo Z; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Hu M; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Khan T; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Murgolo N; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Zhao L; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Penington JS; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Reaksudsan K; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Jarman K; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Dietrich MH; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Richardson L; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Guo KY; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Lopaticki S; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Tham WH; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Rottmann M; Swiss Tropical and Public Health Institute, Basel 4002, Switzerland.
  • Papenfuss T; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Robbins JA; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Boddey JA; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Sleebs BE; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • Sabroux HJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia.
  • McCauley JA; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Olsen DB; Merck & Co., Inc., 770 Sumneytown Pike, West Point, PA 19486, USA. Electronic address: david_olsen@merck.com.
  • Cowman AF; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; University of Melbourne, Melbourne, VIC 3010, Australia. Electronic address: cowman@wehi.edu.au.
Cell Host Microbe ; 27(4): 642-658.e12, 2020 04 08.
Article em En | MEDLINE | ID: mdl-32109369
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 3_ND Problema de saúde: 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 3_malaria Assunto principal: Ácido Aspártico Endopeptidases / Malária / Antimaláricos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Host Microbe Assunto da revista: MICROBIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 3_ND Problema de saúde: 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 3_malaria Assunto principal: Ácido Aspártico Endopeptidases / Malária / Antimaláricos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Host Microbe Assunto da revista: MICROBIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália