Ofranergene obadenovec (VB-111) in platinum-resistant ovarian cancer; favorable response rates in a phase I/II study are associated with an immunotherapeutic effect.

Arend, Rebecca C; Beer, Hannah M; Cohen, Yael C; Berlin, Suzanne; Birrer, Michael J; Campos, Susana M; Rachmilewitz Minei, Tamar; Harats, Dror; Wall, Jaclyn A; Foxall, McKenzie E; Penson, Richard T

Arend, Rebecca C; Beer, Hannah M; Cohen, Yael C; Berlin, Suzanne; Birrer, Michael J; Campos, Susana M; Rachmilewitz Minei, Tamar; Harats, Dror; Wall, Jaclyn A; Foxall, McKenzie E; Penson, Richard T.

Afiliação

Arend RC; University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Beer HM; University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Cohen YC; VBL Therapeutics, Modiin, Israel.
Berlin S; Dana Farber Cancer Institute, York, ME, USA.
Birrer MJ; University of Arkansas for Medical Sciences, Little Rock, AK, USA.
Campos SM; Dana Farber Cancer Institute, York, ME, USA.
Rachmilewitz Minei T; VBL Therapeutics, Modiin, Israel.
Harats D; VBL Therapeutics, Modiin, Israel.
Wall JA; University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Foxall ME; University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Penson RT; Massachusetts General Hospital, Boston, MA, USA. Electronic address: rpenson@partners.org.

Gynecol Oncol ; 157(3): 578-584, 2020 06.

Article em En | MEDLINE | ID: mdl-32265057

Assuntos

Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Imunoterapia/métodos; Neoplasias Ovarianas/tratamento farmacológico; Idoso; Protocolos de Quimioterapia Combinada Antineoplásica/farmacologia; Bleomicina/farmacologia; Bleomicina/uso terapêutico; Cisplatino/farmacologia; Cisplatino/uso terapêutico; Feminino; Humanos; Pessoa de Meia-Idade; Vimblastina/farmacologia; Vimblastina/uso terapêutico

Palavras-chave

Anti-angiogenic; Gene therapy; Immunotherapeutic; Platinum-resistant; Platinum-resistant ovarian cancer; VB-111

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Protocolos de Quimioterapia Combinada Antineoplásica / Imunoterapia Tipo de estudo: Clinical_trials / Risk_factors_studies Limite: Aged / Female / Humans / Middle aged Idioma: En Revista: Gynecol Oncol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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