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Engineering chimeric diterpene synthases and isoprenoid biosynthetic pathways enables high-level production of miltiradiene in yeast.
Hu, Tianyuan; Zhou, Jiawei; Tong, Yuru; Su, Ping; Li, Xinlin; Liu, Yuan; Liu, Nan; Wu, Xiaoyi; Zhang, Yifeng; Wang, Jiadian; Gao, Linhui; Tu, Lichan; Lu, Yun; Jiang, Zhouqian; Zhou, Yongjin J; Gao, Wei; Huang, Luqi.
Afiliação
  • Hu T; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China; School of Pharmaceutical Sciences, Capital Medical University, Beijing, 100069, China.
  • Zhou J; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Tong Y; School of Pharmaceutical Sciences, Capital Medical University, Beijing, 100069, China.
  • Su P; Department of Chemistry, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Li X; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Liu Y; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Liu N; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Wu X; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Zhang Y; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Wang J; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Gao L; Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
  • Tu L; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Lu Y; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Jiang Z; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Zhou YJ; Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
  • Gao W; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China; School of Pharmaceutical Sciences, Capital Medical University, Beijing, 100069, China; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, 100069, China. Electronic add
  • Huang L; State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Metab Eng ; 60: 87-96, 2020 07.
Article em En | MEDLINE | ID: mdl-32268192
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Terpenos / Diterpenos / Proteínas Mutantes Quiméricas / Engenharia Metabólica Idioma: En Revista: Metab Eng Assunto da revista: ENGENHARIA BIOMEDICA / METABOLISMO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Terpenos / Diterpenos / Proteínas Mutantes Quiméricas / Engenharia Metabólica Idioma: En Revista: Metab Eng Assunto da revista: ENGENHARIA BIOMEDICA / METABOLISMO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China