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Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Genes.
Kelsen, Judith R; Dawany, Noor; Conrad, Maire A; Karakasheva, Tatiana A; Maurer, Kelly; Wei, Jane M; Uman, Selen; Dent, Maiah H; Behera, Rithika; Bryant, Laura M; Ma, Xianghui; Moreira, Leticia; Chatterji, Priya; Shraim, Rawan; Merz, Audrey; Mizuno, Rei; Simon, Lauren A; Muir, Amanda B; Giraudo, Claudio; Behrens, Edward M; Whelan, Kelly A; Devoto, Marcella; Russo, Pierre A; Andres, Sarah F; Sullivan, Kathleen E; Hamilton, Kathryn E.
Afiliação
  • Kelsen JR; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Dawany N; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Conrad MA; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Karakasheva TA; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Maurer K; Division of Allergy Immunology, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Wei JM; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Uman S; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.
  • Dent MH; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Behera R; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Bryant LM; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Ma X; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Moreira L; Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red en Enfermedades Hepaticas y Digestivas (CIBERehd), IDIBAPS, University of Barcelona, Catalonia, Spain.
  • Chatterji P; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States.
  • Shraim R; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Merz A; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Mizuno R; Department of Medicine, Gastroenterology Division, University of Pennsylvania, Philadelphia, PA, United States.
  • Simon LA; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Muir AB; Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Giraudo C; Department of Microbiology and Immunology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States.
  • Behrens EM; Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Whelan KA; Fels Institute for Cancer Research & Molecular Biology, Department of Pathology and Laboratory Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
  • Devoto M; Division of Genetics, Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
  • Russo PA; Division of Anatomic Pathology, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Andres SF; Department of Pediatrics, Oregon Health & Science University, Portland, OR, United States.
  • Sullivan KE; Department of Translational and Precision Medicine, University of Rome Sapienza, Rome, Italy.
  • Hamilton KE; Division of Allergy Immunology, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Inflamm Bowel Dis ; 27(2): 256-267, 2021 01 19.
Article em En | MEDLINE | ID: mdl-32556182

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Organoides / Apresentação de Antígeno Tipo de estudo: Risk_factors_studies Limite: Child / Humans Idioma: En Revista: Inflamm Bowel Dis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Organoides / Apresentação de Antígeno Tipo de estudo: Risk_factors_studies Limite: Child / Humans Idioma: En Revista: Inflamm Bowel Dis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
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