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The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates.
Alaei, Mohammadreza; Rohani, Farzaneh; Norouzi, Elahe; Hematian Boroujeni, Nahid; Tafreshi, Roya Isa; Salehiniya, Hamid; Soheilipour, Fahimeh.
Afiliação
  • Alaei M; Department of Pediatric Endocrinology and Metabolism, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Rohani F; Pediatric Growth and Development Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Science, Tehran, Iran.
  • Norouzi E; Department of Pediatrics, Iran University of Medical Sciences, Tehran, Iran.
  • Hematian Boroujeni N; Department of Pediatrics, Iran University of Medical Sciences, Tehran, Iran.
  • Tafreshi RI; Department of Pediatrics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Salehiniya H; Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.
  • Soheilipour F; Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran.
Article em En | MEDLINE | ID: mdl-32582020
ABSTRACT
Background and

Objectives:

Clitoromegaly is an important parameter in the evaluation of ambiguous genitalia in neonates, but the normative data for clitoral size in newborns have racial/ethnic differences. The present study aimed to determine clitoral length (CL) and clitoral width (CW) values and establish cutoff measurement to define clitoromegaly in both term and preterm Iranian neonates for the first time.

Methods:

A total number of 580 female newborn infants delivered at 28-42 weeks of gestation were enrolled in the study, and their CL and CW were measured on the first 72 h of birth. Data about birth weight (BW), body length (BL), and head circumference (HC) of newborns; mothers' age; and gestational age (GA) were recorded, too. Results were presented as mean ± standard deviation (SD) for quantitative variables and were summarized by frequency (percentage) for categorical variables. Backward stepwise regression analysis was used for prediction of CL and CW.

Results:

Among 580 Iranian female newborns studied, 187 were term neonates and the other 393 newborns were preterm. Mean ± SD values of CL were 6.11 ± 0.39 mm in term infants and 5.45 ± 0.64 mm in preterm infants (P < 0.001). Mean ± SD values of CW were 4.22 ± 0.43 in term infants and 3.68 ± 0.53 in preterm infants (P < 0.001). Regression analysis showed that CL was correlated with GA considered by last menstrual period, BL, BW, and HC; and CW was associated with GA, BL, and BW.

Conclusion:

This study suggests normative values (mean + 1, 2, and 3 SD) of CL and CW according to GA, which can be used as a reference for Middle East's newborns, especially Iranian newborn babies.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos do Desenvolvimento Sexual / Clitóris / Nomogramas Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Newborn País/Região como assunto: Asia Idioma: En Revista: Front Endocrinol (Lausanne) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Irã

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos do Desenvolvimento Sexual / Clitóris / Nomogramas Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Newborn País/Região como assunto: Asia Idioma: En Revista: Front Endocrinol (Lausanne) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Irã
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