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The positive effect of selective prostaglandin E2 receptor EP2 and EP4 blockade on cystogenesis in vitro is counteracted by increased kidney inflammation in vivo.
Lannoy, Morgane; Valluru, Manoj K; Chang, Lijun; Abdela-Ali, Fatima; Peters, Dorien J M; Streets, Andrew J; Ong, Albert C M.
Afiliação
  • Lannoy M; Kidney Genetics Group, Academic Nephrology Unit, University of Sheffield Medical School, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield, UK.
  • Valluru MK; Kidney Genetics Group, Academic Nephrology Unit, University of Sheffield Medical School, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield, UK.
  • Chang L; Kidney Genetics Group, Academic Nephrology Unit, University of Sheffield Medical School, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield, UK.
  • Abdela-Ali F; Kidney Genetics Group, Academic Nephrology Unit, University of Sheffield Medical School, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield, UK.
  • Peters DJM; Department of Human Genetics, Leiden University Medical Center (LUMC), Leiden, The Netherlands.
  • Streets AJ; Kidney Genetics Group, Academic Nephrology Unit, University of Sheffield Medical School, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield, UK.
  • Ong ACM; Kidney Genetics Group, Academic Nephrology Unit, University of Sheffield Medical School, Sheffield, UK; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield Medical School, Sheffield, UK. Electronic address: a.ong@sheffield.ac.uk.
Kidney Int ; 98(2): 404-419, 2020 08.
Article em En | MEDLINE | ID: mdl-32622526

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dinoprostona / Receptores de Prostaglandina E Subtipo EP2 Limite: Animals / Humans Idioma: En Revista: Kidney Int Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dinoprostona / Receptores de Prostaglandina E Subtipo EP2 Limite: Animals / Humans Idioma: En Revista: Kidney Int Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
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