Structural and functional studies of <i>Arabidopsis thaliana</i> legumain beta reveal isoform specific mechanisms of activation and substrate recognition.

Dall, Elfriede; Zauner, Florian B; Soh, Wai Tuck; Demir, Fatih; Dahms, Sven O; Cabrele, Chiara; Huesgen, Pitter F; Brandstetter, Hans

Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition.

Dall, Elfriede; Zauner, Florian B; Soh, Wai Tuck; Demir, Fatih; Dahms, Sven O; Cabrele, Chiara; Huesgen, Pitter F; Brandstetter, Hans.

Afiliação

Dall E; Department of Biosciences, University of Salzburg, Salzburg, Austria. Electronic address: elfriede.dall@sbg.ac.at.
Zauner FB; Department of Biosciences, University of Salzburg, Salzburg, Austria.
Soh WT; Department of Biosciences, University of Salzburg, Salzburg, Austria.
Demir F; Central Institute for Engineering, Electronics and Analytics, ZEA-3, Forschungszentrum Jülich, Jülich, Germany.
Dahms SO; Department of Biosciences, University of Salzburg, Salzburg, Austria.
Cabrele C; Department of Biosciences, University of Salzburg, Salzburg, Austria.
Huesgen PF; Central Institute for Engineering, Electronics and Analytics, ZEA-3, Forschungszentrum Jülich, Jülich, Germany; CECAD, Medical Faculty and University Hospital, University of Cologne, Cologne, Germany; Institute for Biochemistry, Faculty of Mathematics and Natural Sciences, University of Cologne, Col
Brandstetter H; Department of Biosciences, University of Salzburg, Salzburg, Austria. Electronic address: hans.brandstetter@sbg.ac.at.

J Biol Chem ; 295(37): 13047-13064, 2020 09 11.

Article em En | MEDLINE | ID: mdl-32719006

Assuntos

Proteínas de Arabidopsis/química; Arabidopsis/enzimologia; Cisteína Endopeptidases/química; Arabidopsis/genética; Proteínas de Arabidopsis/genética; Proteínas de Arabidopsis/metabolismo; Sítios de Ligação; Cristalografia por Raios X; Cisteína Endopeptidases/genética; Cisteína Endopeptidases/metabolismo; Isoenzimas/química; Isoenzimas/genética; Isoenzimas/metabolismo

Palavras-chave

crystal structure; cysteine protease; pH regulation; plant biochemistry; protein stability; structural biology; transpeptidation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína Endopeptidases / Arabidopsis / Proteínas de Arabidopsis Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article

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